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Aamer Saeed
Researcher at Quaid-i-Azam University
Publications - 628
Citations - 8999
Aamer Saeed is an academic researcher from Quaid-i-Azam University. The author has contributed to research in topics: Crystal structure & Chemistry. The author has an hindex of 33, co-authored 570 publications receiving 6148 citations. Previous affiliations of Aamer Saeed include Leibniz University of Hanover & King's College London.
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Recent trends in chemistry, structure, and various applications of 1-acyl-3-substituted thioureas: a detailed review
TL;DR: The interest in acyl thioureas has continually been escalating owing to their extensive applications in diverse fields, such as synthetic precursors of new heterocycles, pharmacological and materials science, and technology as discussed by the authors .
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Isonicotinohydrazones as inhibitors of alkaline phosphatase and ecto-5'-nucleotidase
Pervaiz Ali Channar,Syed Jawad Ali Shah,Sidra Hassan,Zaib un Nisa,Joanna Lecka,Jean Sévigny,Jürgen Bajorath,Aamer Saeed,Jamshed Iqbal +8 more
TL;DR: The most potent inhibitor of h‐e5′NT was derivative (E)‐N′‐(1‐(3‐(4‐fluorophenyl)‐5‐phenyl‐4,5‐dihydro‐1H‐pyrazol‐1‐yl)ethylidene)isonicotinohydrazide (3j), whereas derivative (3g) exhibited significant inhibitory activity against r‐e 5′NT.
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Developing new hybrid scaffold for urease inhibition based on carbazole-chalcone conjugates: Synthesis, assessment of therapeutic potential and computational docking analysis
Madiha Kazmi,Imtiaz Khan,Ajmal Khan,Sobia Ahsan Halim,Aamer Saeed,Saifullah Mehsud,Ahmed Al-Harrasi,Aliya Ibrar,Aliya Ibrar +8 more
TL;DR: The present study demonstrates the successful synthesis of carbazole-chalcone hybrids (4a-n) in good yields and evaluation of the preliminary in vitro biological results showed that selected members of the investigated library of hybrid compounds possess excellent urease inhibitory efficacy.
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Synthesis, molecular docking and biological evaluation of new thiazolopyrimidine carboxylates as potential antidiabetic and antibacterial agents
TL;DR: The current study is expected to provide useful insights into the design of antidiabetic and antibacterial drugs, and understanding the mechanism by which such drugs interact with RNA and diabetes targets and exert their biochemical action.
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New prospects for the development of selective inhibitors of α-glucosidase based on coumarin-iminothiazolidinone hybrids: Synthesis, in-vitro biological screening and molecular docking analysis
TL;DR: These new structural leads based on the hybrid pharmacophores could be developed as potential inhibitors of α-glucosidase for treating postprandial hyperglycemia.