Abhinay Gontu

TL;DR: It is concluded that anti-RBD or anti-ECD IgG titers can serve as a surrogate for VN titers to identify suitable plasma donors to provide critical information about protection against COVID-19 disease.

TL;DR: In this article, a two-step framework was introduced to classify and quantitatively predict binding affinity changes using the decomposed energy terms as descriptors, achieving a validation accuracy of 82.8% for single-amino acid substitution variants of the RBD as worsening or improving binding affinity for hACE2 and a correlation coefficient of 0.73 between predicted and experimentally calculated changes in binding affinities.

TL;DR: This comprehensive review of current knowledge of SA receptor distribution among animal species and the range of viruses that use SAs as receptors can inform targeted surveillance of domestic and wild animals to prevent the future emergence of zoonotic viruses.

TL;DR: These studies provide strong evidence of infection of free-living white-tailed deer with the SARS-CoV-2 B. 1.1.529 Omicron VoC and highlight an urgent need for comprehensive surveillance of susceptible animal species to identify ecological transmission networks and better assess the potential risks of spillback to humans.

TL;DR: In this paper, the authors studied the response trajectories of antibodies directed to the SARS-CoV-2 surface spike glycoprotein and in vitro SARS CoV2 live virus neutralizing titers in 175 convalescent donors longitudinally sampled for up to 142 days post onset of symptoms.