A
Achille P. Caputi
Researcher at University of Messina
Publications - 407
Citations - 19416
Achille P. Caputi is an academic researcher from University of Messina. The author has contributed to research in topics: Nitrotyrosine & Artery occlusion. The author has an hindex of 74, co-authored 405 publications receiving 18740 citations. Previous affiliations of Achille P. Caputi include Queen Mary University of London & University of Salerno.
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Journal ArticleDOI
Glycogen synthase kinase-3β inhibition attenuates the degree of arthritis caused by type II collagen in the mouse
Salvatore Cuzzocrea,Emanuela Mazzon,Rosanna Di Paola,Carmelo Muià,Concetta Crisafulli,Laura Dugo,Marika Collin,Domenico Britti,Achille P. Caputi,Christoph Thiemermann +9 more
TL;DR: It is demonstrated that GSK-3beta inhibition exerts an anti-inflammatory effect during chronic inflammation and is able to ameliorate the tissue damage associated with CIA.
Journal ArticleDOI
17β-Estradiol Antiinflammatory Activity in Carrageenan-Induced Pleurisy
Salvatore Cuzzocrea,Sabrina Santagati,Lidia Sautebin,Emanuela Mazzon,Giusi Calabrò,Ivana Serraino,Achille P. Caputi,Adriana Maggi +7 more
TL;DR: It is shown that, in carrageenan treatment of ovariectomized rats, prior exposure to E2 significantly attenuated inflammatory response as measured by histological examination and exudate production.
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Superoxide: a key player in hypertension
Salvatore Cuzzocrea,Emanuela Mazzon,Laura Dugo,Rosanna Di Paola,Achille P. Caputi,Daniela Salvemini +5 more
TL;DR: The data suggest that overt production of superoxide in SHR couples with nitric oxide, reducing its function and leading to a loss of blood vessel tone and hypertension.
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Effects of tempol, a membrane-permeable radical scavenger, in a gerbil model of brain injury
S. Cuzzocrea,Michelle C. McDonald,Emanuela Mazzon,Dilani Siriwardena,Giuseppina Costantino,Francesco Fulia,G. Cucinotta,Eloisa Gitto,S. Cordaro,Ignazio Barberi,A. De Sarro,Achille P. Caputi,Christoph Thiemermann +12 more
TL;DR: This is the first evidence that the membrane-permeable, radical scavenger tempol reduces the cerebral injury caused by transient, cerebral ischemia in vivo.
Journal ArticleDOI
The cyclopentenone prostaglandin 15-deoxy-Δ12,14- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat
Salvatore Cuzzocrea,Angela Ianaro,Nicole S. Wayman,Emanuela Mazzon,Barbara Pisano,Laura Dugo,Ivana Serraino,Rosanna Di Paola,Prabal K. Chatterjee,Massimo Di Rosa,Achille P. Caputi,Christoph Thiemermann +11 more
TL;DR: In this article, the effects of 15d-PGJ2 in rats subjected to experimental colitis were investigated and it was shown that 15dPGJJ2 significantly reduced the degree of haemorrhagic diarrhoea and weight loss caused by intra-colonic instillation of dinitrobenzene sulphonic acid (DNBS).