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Achille P. Caputi

Researcher at University of Messina

Publications -  407
Citations -  19416

Achille P. Caputi is an academic researcher from University of Messina. The author has contributed to research in topics: Nitrotyrosine & Artery occlusion. The author has an hindex of 74, co-authored 405 publications receiving 18740 citations. Previous affiliations of Achille P. Caputi include Queen Mary University of London & University of Salerno.

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Prescribing pattern of drugs in the treatment of osteoarthritis in Italian general practice: the effect of rofecoxib withdrawal.

TL;DR: Rofecoxib withdrawal has markedly changed the prescribing pattern of drugs that are used in OA-related pain treatment, with a striking decrease of coxib use in Italian general practice.
Journal Article

Absence of endogeneous interleukin-10 enhances the evolution of murine type-II collagen-induced arthritis.

TL;DR: It is demonstrated that endogenous IL-10 exerts an anti-inflammatory role during chronic inflammation and tissue damage associated with collagen-induced arthritis, possibly by regulating neutrophil recruitment, and the subsequent cytokine and oxidant generation.
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Effect of melatonin on cellular energy depletion mediated by peroxynitrite and poly (ADP-ribose) synthetase activation in an acute model of inflammation.

TL;DR: In vivo melatonin treatment significantly reduced peroxynitrite formation in a dose‐dependent manner and prevented the appearance of DNA damage, decrease in mitochondrial respiration, loss of cellular levels of NAD+, and PARS activation, which supports the view that the antioxidant and anti‐inflammatory effect of melatonin is also correlated with the inhibition of peroxlynitrite production and Pars activation.