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Achille P. Caputi
Researcher at University of Messina
Publications - 407
Citations - 19416
Achille P. Caputi is an academic researcher from University of Messina. The author has contributed to research in topics: Nitrotyrosine & Artery occlusion. The author has an hindex of 74, co-authored 405 publications receiving 18740 citations. Previous affiliations of Achille P. Caputi include Queen Mary University of London & University of Salerno.
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Role of constitutive nitric oxide synthase and peroxynitrite production in a rat model of splanchnic artery occlusion shock
TL;DR: The results suggest that during splanchnic artery occlusion shock peroxynitrite formation is likely to be correlated with nitric oxide production from constitutiveNitric oxide synthase activation rather than from the inducible isoform enzyme.
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Effects of intracerebroventricular leptin administration on food intake, body weight gain and diencephalic nitric oxide synthase activity in the mouse
Gioacchino Calapai,Francesco Corica,Alessandro Allegra,Andrea Corsonello,Lidia Sautebin,Tiziana De Gregorio,Massimo Di Rosa,Giuseppina Costantino,Michele Buemi,Achille P. Caputi +9 more
TL;DR: The results suggest that the brain L‐arginine/NO pathway may be involved in the central effect of leptin on feeding behaviour and body weight gain in mice.
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5-Lipoxygenase modulates colitis through the regulation of adhesion molecule expression and neutrophil migration.
Salvatore Cuzzocrea,Antonietta Rossi,Emanuela Mazzon,Rosanna Di Paola,Tiziana Genovese,Carmelo Muià,Achille P. Caputi,Lidia Sautebin +7 more
TL;DR: It is shown that 5-LO modulates neutrophil infiltration in experimental colitis through the expression of adhesion molecules, which is a significant reduction of the degree of colon injury and the rise in myeloperoxidase (MPO) activity (mucosa).
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Tempol, a membrane-permeable radical scavenger, reduces dinitrobenzene sulfonic acid-induced colitis
Salvatore Cuzzocrea,Michelle C. McDonald,Emanuela Mazzon,Laura Dugo,Valeria Lepore,Maria Teresa Fonti,Antonio Ciccolo,Maria Luisa Terranova,Achille P. Caputi,Christoph Thiemermann +9 more
TL;DR: It is suggested that membrane-permeable radical scavengers, such as tempol, exert beneficial effects in experimental colitis and may, hence, be useful in the treatment of inflammatory bowel disease.
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Role of peroxynitrite and activation of poly (ADP‐ribose) synthetase in the vascular failure induced by zymosan‐activated plasma
Salvatore Cuzzocrea,Salvatore Cuzzocrea,Basilia Zingarelli,Michael O'Connor,Andrew L. Salzman,Achille P. Caputi,Csaba Szabó +6 more
TL;DR: The data obtained suggest that zymosan‐activated plasma causes vascular dysfunction by inducing the simultaneous formation of superoxide and NO, which combines to form peroxynitrite, which, in turn, causes DNA injury and PARS activation.