A
Achille P. Caputi
Researcher at University of Messina
Publications - 407
Citations - 19416
Achille P. Caputi is an academic researcher from University of Messina. The author has contributed to research in topics: Nitrotyrosine & Artery occlusion. The author has an hindex of 74, co-authored 405 publications receiving 18740 citations. Previous affiliations of Achille P. Caputi include Queen Mary University of London & University of Salerno.
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Protective effects of Celecoxib on lung injury and red blood cells modification induced by carrageenan in the rat.
Salvatore Cuzzocrea,Emanuela Mazzon,Lidia Sautebin,Laura Dugo,Ivana Serraino,Angela De Sarro,Achille P. Caputi +6 more
TL;DR: Results clearly confirmed that COX-2 plays a critical role in the development of theinflammatory response by altering key components of the inflammatory cascade and offers a therapeutic approach for the management of various inflammatory diseases.
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The Burden of Nephrotoxic Drug Prescriptions in Patients with Chronic Kidney Disease: A Retrospective Population-Based Study in Southern Italy
Ylenia Ingrasciotta,Janet Sultana,Francesco Giorgianni,Achille P. Caputi,Vincenzo Arcoraci,Daniele Ugo Tari,Claudio Linguiti,Margherita Perrotta,Andrea Nucita,Fabio Pellegrini,Andrea Fontana,Lorenzo Cavagna,Domenico Santoro,Gianluca Trifirò +13 more
TL;DR: Contraindicated nephrotoxic drugs were highly prescribed in CKD patients from a general population of Southern Italy during the years 2006–2011, with nimesulide and diclofenac being most frequently used.
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Absence of endogenous interleukin-6 enhances the inflammatory response during acute pancreatitis induced by cerulein in mice.
Salvatore Cuzzocrea,Emanuela Mazzon,Laura Dugo,Tommaso Centorrino,Antonio Ciccolo,Michelle C. McDonald,Agelina de Sarro,Achille P. Caputi,Christoph Thiemermann +8 more
TL;DR: Data demonstrate that endogenous IL-6 exerts an anti-inflammatory role during acute pancreatitis, possibly by regulating the expression of adhesion molecules, the subsequent adhesion and activation of neutrophils and finally the generation of cytokine and reactive oxygen or nitrogen species.
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Role of IL-10 in Hepatocyte Tight Junction Alteration in Mouse Model of Experimental Colitis
TL;DR: It is suggested that the absence of IL-10 may represent an important pathophysiological mechanism of hepatobiliary injuries and cholestasis observed in patients with IBD.
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Tacrolimus limits polymorphonuclear leucocyte accumulation and protects against myocardial ischaemia- reperfusion injury.
Francesco Squadrito,Domenica Altavilla,Giovanni Squadrito,Antonino Saitta,Barbara Deodato,Mariarita Arlotta,Letteria Minutoli,Cristina Quartarone,Marcella Ferlito,Achille P. Caputi +9 more
TL;DR: The present data suggest that tacrolimus blocks the early activation of the transcription factor NF- kappaB, suppresses ICAM-1 gene activation, reduces leukocyte accumulation and protects against myocardial ischaemia-reperfusion injury.