A
Agus Salim
Researcher at Baker IDI Heart and Diabetes Institute
Publications - 217
Citations - 6770
Agus Salim is an academic researcher from Baker IDI Heart and Diabetes Institute. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 33, co-authored 161 publications receiving 5268 citations. Previous affiliations of Agus Salim include National University of Singapore & Australian National University.
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Journal ArticleDOI
FunRich: An open access standalone functional enrichment and interaction network analysis tool
Mohashin Pathan,Shivakumar Keerthikumar,Ching-Seng Ang,Lahiru Gangoda,Camelia Quek,Nicholas A. Williamson,Dmitri Mouradov,Oliver M. Sieber,Oliver M. Sieber,Richard J. Simpson,Agus Salim,Antony Bacic,Andrew F. Hill,Andrew F. Hill,David A. Stroud,Michael T. Ryan,Johnson I. Agbinya,John M. Mariadason,Antony W. Burgess,Antony W. Burgess,Suresh Mathivanan +20 more
TL;DR: FunRich is an open access, standalone functional enrichment and network analysis tool that permits for the tool to be exploited as a skeleton for enrichment analysis irrespective of the data type or organism used.
Journal ArticleDOI
Smoking as a Risk Factor for Dementia and Cognitive Decline: A Meta-Analysis of Prospective Studies
TL;DR: It is concluded that elderly smokers have increased risks of dementia and cognitive decline and the groups were not different regarding risk of vascular dementia or any dementia.
Journal ArticleDOI
Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis
Peter Savas,Balaji Virassamy,Chengzhong Ye,Agus Salim,Agus Salim,Christopher P. Mintoff,Franco Caramia,Roberto Salgado,David J Byrne,Zhi Ling Teo,Zhi Ling Teo,Sathana Dushyanthen,Ann Byrne,Lironne Wein,Stephen J Luen,Catherine Poliness,Sophie Nightingale,Anita S Skandarajah,Anita S Skandarajah,David E. Gyorki,Chantel M Thornton,Paul A. Beavis,Paul A. Beavis,Stephen B. Fox,Phillip K. Darcy,Phillip K. Darcy,Terence P. Speed,Terence P. Speed,Laura K. Mackay,Paul J Neeson,Paul J Neeson,Sherene Loi,Sherene Loi +32 more
TL;DR: Detailed, high-dimensional characterization of T cells in breast cancer reveals activated TRM population and a gene signature associated with improved prognosis and suggest that CD8+ TRM cells contribute to BC immunosurveillance and are the key targets of modulation by immune checkpoint inhibition.
Journal ArticleDOI
Accessory subunits are integral for assembly and function of human mitochondrial complex I
David A. Stroud,Elliot Surgenor,Luke E. Formosa,Luke E. Formosa,Boris Reljic,Ann E. Frazier,Marris G. Dibley,Laura D. Osellame,Tegan Stait,Traude H. Beilharz,David R. Thorburn,David R. Thorburn,Agus Salim,Michael T. Ryan +13 more
TL;DR: It is shown that 25 subunits are strictly required for assembly of a functional complex and 1 subunit is essential for cell viability, and coupling gene-editing technology with proteomics represents a powerful tool for dissecting large multi-subunit complexes and enables the study of complex dysfunction at a cellular level.
Journal ArticleDOI
Statistical challenges associated with detecting copy number variations with next-generation sequencing
TL;DR: This review describes and discusses areas of potential biases in CNV detection for each of the four broad methods using NGS, and focuses on issues pertaining to mappability, GC-content bias, quality control measures of reads and difficulty in identifying duplications.