scispace - formally typeset
L

Laura D. Osellame

Researcher at La Trobe University

Publications -  27
Citations -  8923

Laura D. Osellame is an academic researcher from La Trobe University. The author has contributed to research in topics: Mitochondrion & Mitochondrial fission. The author has an hindex of 18, co-authored 25 publications receiving 7609 citations. Previous affiliations of Laura D. Osellame include Monash University & Discovery Institute.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

MiD49 and MiD51, new components of the mitochondrial fission machinery

Catherine S Palmer, +5 more
- 01 Jun 2011 - 
TL;DR: Overexpression of MiD49/51 seems to sequester Drp1 from functioning at mitochondria and cause fused tubules to associate with actin, resulting in unopposed fusion.
Journal ArticleDOI

Cellular and molecular mechanisms of mitochondrial function

Laura D. Osellame, +2 more
- 01 Dec 2012 - 
TL;DR: Mitochondria are membrane bound organelles present in almost all eukaryotic cells and contribute to many processes central to cellular function and dysfunction including calcium signalling, cell growth and differentiation, cell cycle control and cell death.
Journal ArticleDOI

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis

Kate McArthur, +38 more
- 23 Feb 2018 - 
TL;DR: This study provides a mechanistic description of mtDNA release from mitochondria during apoptosis, and suggests that mtDNA is found outside the mitochondria—and, indeed, outside the cell—in a wide range of circumstances.
Journal ArticleDOI

Accessory subunits are integral for assembly and function of human mitochondrial complex I

David A. Stroud, +13 more
- 06 Oct 2016 - 
TL;DR: It is shown that 25 subunits are strictly required for assembly of a functional complex and 1 subunit is essential for cell viability, and coupling gene-editing technology with proteomics represents a powerful tool for dissecting large multi-subunit complexes and enables the study of complex dysfunction at a cellular level.