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Alain Lefevre-Utile
Researcher at University of Paris
Publications - 22
Citations - 526
Alain Lefevre-Utile is an academic researcher from University of Paris. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 7, co-authored 16 publications receiving 289 citations. Previous affiliations of Alain Lefevre-Utile include Paris Descartes University & Necker-Enfants Malades Hospital.
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Journal ArticleDOI
Coronavirus Disease 2019 Pandemic: Impact Caused by School Closure and National Lockdown on Pediatric Visits and Admissions for Viral and Nonviral Infections-a Time Series Analysis.
François Angoulvant,Naim Ouldali,David D. Yang,Mathilde Filser,Vincent Gajdos,Vincent Gajdos,Alexis Rybak,Romain Guedj,Valérie Soussan-Banini,Romain Basmaci,Alain Lefevre-Utile,Dominique Brun-Ney,Laure Beaujouan,David Skurnik,David Skurnik +14 more
TL;DR: A time series analysis revealed that the COVID-19 lockdown and school closure were associated with a significant decrease in infectious diseases disseminated through airborne or fecal-oral transmissions, including common cold, gastro-enteritis, bronchiolitis, acute otitis.
Journal ArticleDOI
Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines
Nicholas Hernandez,Giorgia Bucciol,Leen Moens,Jérémie Le Pen,Mohammad Shahrooei,Ekaterini Goudouris,Afshin Shirkani,Majid Changi-Ashtiani,Hassan Rokni-Zadeh,Esra Hazar Sayar,Ismail Reisli,Alain Lefevre-Utile,Dick Zijlmans,Andrea Jurado,Ruben Pholien,Scott Drutman,Serkan Belkaya,Aurélie Cobat,Robbert Boudewijns,Dirk Jochmans,Johan Neyts,Yoann Seeleuthner,Yoann Seeleuthner,Lazaro Lorenzo-Diaz,Lazaro Lorenzo-Diaz,Chibuzo U Enemchukwu,Ian Tietjen,Hans Heinrich Hoffmann,Mana Momenilandi,Laura Pöyhönen,Marilda M. Siqueira,Sheila Maria Barbosa de Lima,Denise Cristina de Souza Matos,Akira Homma,Maria de Lourdes de Sousa Maia,Tamiris Azamor da Costa Barros,Patrícia Mouta Nunes de Oliveira,Emersom Ciclini Mesquita,Rik Gijsbers,Shen-Ying Zhang,Shen-Ying Zhang,Shen-Ying Zhang,Stephen J. Seligman,Stephen J. Seligman,Laurent Abel,Laurent Abel,Laurent Abel,Paul J. Hertzog,Nico Marr,Nico Marr,Reinaldo de Menezes Martins,Isabelle Meyts,Isabelle Meyts,Qian Zhang,Margaret R. MacDonald,Charles M. Rice,Jean-Laurent Casanova,Emmanuelle Jouanguy,Emmanuelle Jouanguy,Emmanuelle Jouanguy,Xavier Bossuyt +60 more
TL;DR: Two unrelated patients with inherited IFNAR1 deficiency who suffered from life-threatening infections following measles or yellow fever virus vaccination and were otherwise healthy are described.
Journal ArticleDOI
Circulating cell-free BRAF V600E as a biomarker in children with Langerhans cell histiocytosis.
Sébastien Héritier,Zofia Hélias-Rodzewicz,Hélène Lapillonne,Nathalie Terrones,Sonia Garrigou,Corinne Normand,Mohamed-Aziz Barkaoui,Jean Miron,Geneviève Plat,Nathalie Aladjidi,Anne Pagnier,Anne Deville,Marion Gillibert-Yvert,Despina Moshous,Alain Lefevre-Utile,Anne Lutun,Catherine Paillard,Caroline Thomas,Eric Jeziorski,Philippe Nizard,Valérie Taly,Jean-François Emile,Jean Donadieu +22 more
TL;DR: In this paper, the authors investigated the detection of the BRAFV600E allele in circulating cell-free (ccf) DNA in a paediatric LCH cohort using a picolitre-droplet digital PCR assay.
Journal ArticleDOI
Incomplete penetrance for isolated congenital asplenia in humans with mutations in translated and untranslated RPSA exons
Alexandre Bolze,Bertrand Boisson,Bertrand Boisson,Bertrand Boisson,Barbara Bosch,Alexander Antipenko,Matthieu Bouaziz,Matthieu Bouaziz,Paul Sackstein,Malik Chaker-Margot,Vincent Barlogis,Tracy A Briggs,Elena Colino,Aurora C. Elmore,Alain Fischer,Ferah Genel,Angela L. Hewlett,Maher Jedidi,Jadranka Kelecic,Renate Krüger,Cheng-Lung Ku,Dinakantha S. Kumararatne,Alain Lefevre-Utile,Sam Loughlin,Nizar Mahlaoui,Susanne Markus,Juan Miguel Garcia,Mathilde Nizon,Matias Oleastro,Małgorzata Pac,Capucine Picard,Capucine Picard,Capucine Picard,Andrew J. Pollard,Carlos Rodríguez-Gallego,Caroline Thomas,Horst von Bernuth,Horst von Bernuth,Austen Worth,Isabelle Meyts,Maurizio Risolino,Licia Selleri,Anne Puel,Anne Puel,Anne Puel,Sebastian Klinge,Laurent Abel,Laurent Abel,Laurent Abel,Jean-Laurent Casanova +49 more
TL;DR: 11 new heterozygous ICA-causing RPSA protein-coding mutations, and the first two mutations in the 5′-UTR of this gene, which disrupt mRNA splicing are described, which can underlie ICA with complete or incomplete penetrance.
Journal ArticleDOI
Mammalian target of rapamycin inhibition counterbalances the inflammatory status of immune cells in patients with chronic granulomatous disease
Aurélie Gabrion,Isabelle Hmitou,Despina Moshous,Despina Moshous,Despina Moshous,Bénédicte Neven,Bénédicte Neven,Bénédicte Neven,Alain Lefevre-Utile,Jean-Sebastien Diana,Felipe Suarez,Capucine Picard,Stéphane Blanche,Stéphane Blanche,Alain Fischer,Marina Cavazzana,Marina Cavazzana,Marina Cavazzana,Fabien Touzot,Fabien Touzot,Fabien Touzot +20 more
TL;DR: Patients with CGD present a consistent inflammatory phenotype defined by a proinflammatory state of mononuclear phagocytes with increased IL‐1&bgr; and TNF‐&agr; content, and a TH17 bias of CD4+ T cells, and an increase in IL‐17A–secreting neutrophil numbers are studied.