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Esra Hazar Sayar
Publications - 10
Citations - 396
Esra Hazar Sayar is an academic researcher. The author has contributed to research in topics: Common variable immunodeficiency & Immunodeficiency. The author has an hindex of 6, co-authored 10 publications receiving 257 citations.
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Journal ArticleDOI
Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant
Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Noé Ramírez-Alejo,Zhi Li,Zhi Li,Etienne Patin,Etienne Patin,Geetha Rao,Gaspard Kerner,Gaspard Kerner,Che Kang Lim,Che Kang Lim,Dimitry N. Krementsov,Nicholas Hernandez,Cindy S. Ma,Cindy S. Ma,Qian Zhang,Qian Zhang,Janet Markle,Rubén Martínez-Barricarte,Kathryn Payne,Robert Fisch,Caroline Deswarte,Caroline Deswarte,Joshua Halpern,Matthieu Bouaziz,Matthieu Bouaziz,Jeanette Mulwa,Durga Sivanesan,Durga Sivanesan,Tomi Lazarov,Rodrigo Naves,Patricia García,Yuval Itan,Yuval Itan,Bertrand Boisson,Bertrand Boisson,Bertrand Boisson,Alix Checchi,Alix Checchi,Fabienne Jabot-Hanin,Fabienne Jabot-Hanin,Aurélie Cobat,Aurélie Cobat,Andrea Guennoun,Carolyn C. Jackson,Carolyn C. Jackson,Sevgi Pekcan,Zafer Caliskaner,Jaime Inostroza,Beatriz Tavares Costa-Carvalho,Jose Antonio Tavares de Albuquerque,Humberto García-Ortiz,Lorena Orozco,Tayfun Ozcelik,Ahmed Abid,Ismail Abderahmani Rhorfi,Hicham Souhi,Hicham Naji Amrani,Adil Zegmout,Frederic Geissmann,Stephen W. Michnick,Ingrid Müller-Fleckenstein,Bernhard Fleckenstein,Anne Puel,Anne Puel,Anne Puel,Michael J. Ciancanelli,Nico Marr,Hassan Abolhassani,Hassan Abolhassani,María Elvira Balcells,Antonio Condino-Neto,Alexis Strickler,Katia Abarca,Cory Teuscher,Hans D. Ochs,Ismail Reisli,Esra Hazar Sayar,Jamila El-Baghdadi,Jacinta Bustamante,Lennart Hammarström,Lennart Hammarström,Lennart Hammarström,Stuart G. Tangye,Stuart G. Tangye,Sandra Pellegrini,Sandra Pellegrini,Lluis Quintana-Murci,Lluis Quintana-Murci,Laurent Abel,Laurent Abel,Laurent Abel,Jean-Laurent Casanova +94 more
TL;DR: Homozygosity for the catalytically inactive P1104A missense variant of the TYK2 Janus kinase selectively disrupts the induction of IFN-γ by IL-23 and is a common monogenic etiology of tuberculosis.
Journal ArticleDOI
Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines
Nicholas Hernandez,Giorgia Bucciol,Leen Moens,Jérémie Le Pen,Mohammad Shahrooei,Ekaterini Goudouris,Afshin Shirkani,Majid Changi-Ashtiani,Hassan Rokni-Zadeh,Esra Hazar Sayar,Ismail Reisli,Alain Lefevre-Utile,Dick Zijlmans,Andrea Jurado,Ruben Pholien,Scott Drutman,Serkan Belkaya,Aurélie Cobat,Robbert Boudewijns,Dirk Jochmans,Johan Neyts,Yoann Seeleuthner,Yoann Seeleuthner,Lazaro Lorenzo-Diaz,Lazaro Lorenzo-Diaz,Chibuzo U Enemchukwu,Ian Tietjen,Hans Heinrich Hoffmann,Mana Momenilandi,Laura Pöyhönen,Marilda M. Siqueira,Sheila Maria Barbosa de Lima,Denise Cristina de Souza Matos,Akira Homma,Maria de Lourdes de Sousa Maia,Tamiris Azamor da Costa Barros,Patrícia Mouta Nunes de Oliveira,Emersom Ciclini Mesquita,Rik Gijsbers,Shen-Ying Zhang,Shen-Ying Zhang,Shen-Ying Zhang,Stephen J. Seligman,Stephen J. Seligman,Laurent Abel,Laurent Abel,Laurent Abel,Paul J. Hertzog,Nico Marr,Nico Marr,Reinaldo de Menezes Martins,Isabelle Meyts,Isabelle Meyts,Qian Zhang,Margaret R. MacDonald,Charles M. Rice,Jean-Laurent Casanova,Emmanuelle Jouanguy,Emmanuelle Jouanguy,Emmanuelle Jouanguy,Xavier Bossuyt +60 more
TL;DR: Two unrelated patients with inherited IFNAR1 deficiency who suffered from life-threatening infections following measles or yellow fever virus vaccination and were otherwise healthy are described.
Journal ArticleDOI
DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency
Timo Volk,Ulrich Pannicke,Ismail Reisli,Alla Bulashevska,Julia Ritter,Andrea Björkman,Alejandro A. Schäffer,Manfred Fliegauf,Esra Hazar Sayar,Ulrich Salzer,Paul Fisch,Dietmar Pfeifer,Michela Di Virgilio,Hongzhi Cao,Fang Yang,Karin Zimmermann,Sevgi Keles,Zafer Caliskaner,S¸ükrü Güner,Detlev Schindler,Lennart Hammarstrom,Marta Rizzi,Michael Hummel,Qiang Pan-Hammarström,Klaus Schwarz,Bodo Grimbacher,Bodo Grimbacher +26 more
TL;DR: It is demonstrated that DCLRE1C mutations can cause a phenotype presenting as only antibody deficiency, which broadens the clinical spectrum associated with ARTEMIS mutations.
Journal ArticleDOI
Type I IFN-related NETosis in ataxia telangiectasia and Artemis deficiency.
Ersin Gul,Esra Hazar Sayar,Bilgi Gungor,Fehime Kara Eroglu,Naz Surucu,Sevgi Keles,Şükrü Nail Güner,Sıddıka Fındık,Esin Alpdundar,Ihsan Cihan Ayanoglu,Basak Kayaoglu,Busra Nur Geckin,Hatice Asena Sanli,Tamer Kahraman,Cengiz Yakicier,Meltem Muftuoglu,Berna Oguz,Deniz Cagdas Ayvaz,Ihsan Gursel,Seza Ozen,Ismail Reisli,Mayda Gursel +21 more
TL;DR: In this paper, the type I IFN-mediated neutrophil activation and extracellular trap formation may contribute to inflammatory manifestations observed in patients with ataxia telangiectasia (AT), Artemis deficiency, and SAVI.
Journal ArticleDOI
How effective are the 6 European Society of Immunodeficiency warning signs for primary immunodeficiency disease
Sevket Arslan,Ramazan Ucar,Ahmet Zafer Caliskaner,Ismail Reisli,Şükrü Nail Güner,Esra Hazar Sayar,Ismail Baloglu +6 more
TL;DR: The ESID warning signs do not specify the need for symptoms to diagnose a PIDs and do not include a comprehensive list of all signs and symptoms of PIDs, so more than infection-centric questions are needed to identify adult patients with immunodeficiencies.