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Alastair Henderson
Researcher at Maidstone and Tunbridge Wells NHS Trust
Publications - 55
Citations - 1206
Alastair Henderson is an academic researcher from Maidstone and Tunbridge Wells NHS Trust. The author has contributed to research in topics: Prostate cancer & Brachytherapy. The author has an hindex of 17, co-authored 54 publications receiving 938 citations. Previous affiliations of Alastair Henderson include Frimley Park Hospital & Maidstone Hospital.
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Journal ArticleDOI
Timing of radiotherapy after radical prostatectomy (RADICALS-RT): a randomised, controlled phase 3 trial
Chris Parker,Noel W. Clarke,Adrian Cook,Howard Kynaston,Peter Meidahl Petersen,Charles Catton,William Cross,John P Logue,Wendy R. Parulekar,Heather Payne,Rajendra Persad,Holly Pickering,Fred Saad,Juliette Anderson,Amit Bahl,David Bottomley,Klaus Brasso,Rohit Chahal,Peter Cooke,Ben Eddy,Stephanie Gibbs,Chee Goh,Sandeep Gujral,Catherine Heath,Alastair Henderson,Ramasamy Jaganathan,Henrik Jakobsen,Nicholas D. James,S.K. Sundaram,Kathryn Lees,Jason F. Lester,Henriette Lindberg,Julian Money-Kyrle,S L Morris,Joe M. O'Sullivan,Peter Ostler,Lisa Owen,Prashant Patel,Alvan Pope,Alvan Pope,Alvan Pope,Rick Popert,Rakesh Raman,Martin Andreas Røder,Ian Sayers,Matthew S. Simms,James M. Wilson,Anjali Zarkar,Mahesh K. B. Parmar,Matthew R. Sydes +49 more
TL;DR: The initial results do not support routine administration of adjuvant radiotherapy after radical prostatectomy, and an observation policy with salvage radiotherapy for PSA biochemical progression should be the current standard after radical Prostate cancer.
Journal ArticleDOI
Extensive transperineal template biopsies of prostate: modified technique and results.
Simon Bott,Alastair Henderson,James E. Halls,Bruce Montgomery,Robert W. Laing,Stephen E.M. Langley +5 more
TL;DR: In men with a clinical suspicion of prostate cancer, but benign or equivocal prostate biopsies, extensive transperineal template biopsy of the prostate is a useful diagnostic tool.
Journal ArticleDOI
Multiparametric MRI to improve detection of prostate cancer compared with transrectal ultrasound-guided prostate biopsy alone: the PROMIS study.
Louise Brown,Hashim U. Ahmed,Hashim U. Ahmed,Rita Faria,Ahmed El-Shater Bosaily,Ahmed El-Shater Bosaily,Rhian Gabe,Richard Kaplan,Mahesh K. B. Parmar,Yolanda Collaco-Moraes,Katie Ward,Richard Hindley,Alex Freeman,Alexander Kirkham,Robert Oldroyd,Chris Parker,Simon Bott,Nick Burns-Cox,Tim Dudderidge,Maneesh Ghei,Alastair Henderson,Rajendra Persad,Derek J. Rosario,Iqbal S. Shergill,Mathias Winkler,Marta Soares,Eldon Spackman,Mark Sculpher,Mark Emberton,Mark Emberton +29 more
TL;DR: Multiparametric magnetic resonance imaging used as a triage test might allow men to avoid unnecessary TRUS-guided biopsy and improve diagnostic accuracy, and the cost-effectiveness of a mpMRI-based diagnostic pathway is estimated.
Journal ArticleDOI
Who Should Be Investigated for Haematuria? Results of a Contemporary Prospective Observational Study of 3556 Patients.
Wei Shen Tan,Wei Shen Tan,Andrew Feber,Rachael Sarpong,Pramit Khetrapal,Simon Rodney,Rumana Jalil,Hugh Mostafid,Joanne Cresswell,James Hicks,Abhay Rane,Alastair Henderson,Dawn Watson,Jacob Cherian,Norman R. Williams,Chris Brew-Graves,John D. Kelly +16 more
TL;DR: The requirement to investigate all patients with visible blood in the urine and an age threshold of ≥60 yr, as recommended in some guidelines, is highlighted, as the investigation of nonvisible blood inThe urine will miss a significant number of urinary tract cancers.
Journal Article
A randomized controlled trial investigating the effects of celecoxib in patients with localized prostate cancer.
Prasanna Sooriakumaran,Helen M. Coley,Stephen B. Fox,Patricia Macanas-Pirard,David P. Lovell,Alastair Henderson,Christopher G. Eden,Paul D Miller,Stephen M. Langley,Robert W. Laing +9 more
TL;DR: A 4 week regimen of celecoxib resulted in measurable biological effects in prostate cancer tissue, which approached statistical significance in a multivariate model and the cell proliferation index approach statistical significance on univariate analysis.