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Tim Dudderidge

Researcher at University of Southampton

Publications -  112
Citations -  5044

Tim Dudderidge is an academic researcher from University of Southampton. The author has contributed to research in topics: Prostate cancer & Cancer. The author has an hindex of 23, co-authored 84 publications receiving 3470 citations. Previous affiliations of Tim Dudderidge include The Royal Marsden NHS Foundation Trust & University Hospital Southampton NHS Foundation Trust.

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Pan-cancer analysis of whole genomes

Peter J. Campbell, +1332 more
- 06 Feb 2020 - 
TL;DR: The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.
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Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

Rosalind A. Eeles, +156 more
- 01 Apr 2013 - 
TL;DR: In this paper, a custom Illumina array (iCOGS) was used to genotype 211,155 SNPs in blood DNA from 25,074 prostate cancer cases and 24,272 controls from the international PRACTICAL Consortium.
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Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

Colin Cooper, +80 more
- 01 Apr 2015 - 
TL;DR: Genome-wide DNA sequencing was used to decrypt the phylogeny of multiple samples from distinct areas of cancer and morphologically normal tissue taken from the prostates of three men, demonstrating the existence of ongoing abnormal mutational processes, consistent with field effects, underlying carcinogenesis.
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A Multicentre Study of 5-year Outcomes Following Focal Therapy in Treating Clinically Significant Nonmetastatic Prostate Cancer

Stephanie Guillaumier, +28 more
- 01 Oct 2018 - 
TL;DR: Focal HIFU therapy for patients with clinically significant prostate cancer that has not spread has a low probability of side effects and is effective at 5 yr, according to a multicentre study of 625 patients undergoing focal therapy using high-intensity focused ultrasound (HIFU).
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Mutational signatures of ionizing radiation in second malignancies.

Sam Behjati, +90 more
- 12 Sep 2016 - 
TL;DR: Two signatures of somatic mutation characterize ionizing radiation exposure irrespective of tumour type, and a significant increase in balanced inversions in radiation-associated tumours is observed.