Albert Mimran

TL;DR: Olmesartan was associated with a delayed onset of microalbuminuria, even though blood-pressure control in both groups was excellent according to current standards.

TL;DR: The results indicate that the overweight condition is associated with renal hyperfiltration and hyperperfusion, irrespective of the presence of hypertension, and that obesity magnifies the effect of hypertension on albuminuria, thus raising the possibility of an increased susceptibility of obese hypertensive patients to the development of renal damage.

TL;DR: Clinical studies comparing the effects of antihypertensives on endothelial function suggest differences and Pharmacokinetic properties of various ACE inhibitors indicate that there are differences in their binding characteristics for tissue ACE.

TL;DR: Results indicate that simvastatin prevented the development of hypertension and cardiovascular hypertrophy together with inhibition of the induced angiotensin II production of ROS.

TL;DR: Pharmacologic studies show that while ACE inhibitors may differ according to their binding affinity for tissue ACE the clinical significance remains to be determined, and that its inhibition may restore endothelial function or prevent endothelial dysfunction.