Alex A. Pollen

TL;DR: A high-quality reference genome assembly for threespine stickleback fish is developed and it is indicated that reuse of globally shared standing genetic variation has an important role in repeated evolution of distinct marine and freshwater sticklebacks, and in the maintenance of divergent ecotypes during early stages of reproductive isolation.

TL;DR: This paper identifies diverse cell types, including multiple progenitor and neuronal subtypes, and identifies EGR1 and FOS as previously unreported candidate targets of Notch signaling in human but not mouse radial glia by microfluidic single-cell capture and low-coverage sequencing of many cells.

TL;DR: The results support a mixed model of topographical, typological, and temporal hierarchies governing cell-type diversity in the developing human telencephalon, including distinct excitatory lineages emerging in rostral and caudal cerebral cortex.

TL;DR: It is suggested that outer radial glia directly support the subventricular niche through local production of growth factors, potentiation of growth factor signals by extracellular matrix proteins, and activation of self-renewal pathways, thereby enabling the developmental and evolutionary expansion of the human neocortex.