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Alexander Dietrich

Researcher at Ludwig Maximilian University of Munich

Publications -  132
Citations -  8613

Alexander Dietrich is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Transient receptor potential channel & TRPC. The author has an hindex of 49, co-authored 120 publications receiving 7689 citations. Previous affiliations of Alexander Dietrich include University of Ulm & University of Marburg.

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Store-operated Ca 2+ entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migration.

TL;DR: It is shown that TRPC1/6 channels are not involved in SOCE and STIM1/2 deficiency resulted in decreased cell proliferation and migration in pmLF, and cell proliferation, migration and nuclear localization of nuclear factor of activated T-cells were decreased.
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TRP channel function in platelet and megakaryocyte: Basic mechanisms and pathophysiological impact.

TL;DR: Transient receptor potential (TRP) proteins form a superfamily of cation channels that are expressed in a wide range of tissues and cell types as mentioned in this paper , and the diversity of functions depends on multiple regulatory mechanisms by which TRP channels regulate Ca2+ entry mechanisms and intracellular Ca 2+ dynamics, either through membrane depolarization involving cation influx or store-and receptor-operated mechanisms.
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TRPC1 Regulates the Activity of a Voltage-Dependent Nonselective Cation Current in Hippocampal CA1 Neurons.

TL;DR: TRPC1 has an inhibitory effect on receptor-operated nonselective cation channels in hippocampal CA1 neurons probably as a result of heterotetramer formation with other TRPC isoforms, and that TRPC1 deletion has only minor effects on dendritic morphology.