A
Alexander J. Lazar
Researcher at University of Texas MD Anderson Cancer Center
Publications - 578
Citations - 55895
Alexander J. Lazar is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Sarcoma & Medicine. The author has an hindex of 93, co-authored 487 publications receiving 38717 citations. Previous affiliations of Alexander J. Lazar include Baylor College of Medicine & Beth Israel Deaconess Medical Center.
Papers
More filters
Journal ArticleDOI
Proficiency Testing of Standardized Samples Shows Very High Interlaboratory Agreement for Clinical Next-Generation Sequencing-Based Oncology Assays.
Jason D. Merker,Kelly A. Devereaux,A. John Iafrate,A. John Iafrate,Suzanne Kamel-Reid,Suzanne Kamel-Reid,Annette S. Kim,Joel T. Moncur,Stephen B. Montgomery,Rakesh Nagarajan,Bryce P. Portier,Mark J. Routbort,Craig Smail,Lea F. Surrey,Patricia Vasalos,Alexander J. Lazar,Neal I. Lindeman +16 more
TL;DR: In this article, next-generation sequencing-based assays are being increasingly used in the clinical setting for the detection of somatic variants in solid tumors, but limited data are available regarding their performance.
Journal ArticleDOI
RNA interference of PARG could inhibit the metastatic potency of colon carcinoma cells via PI3-kinase/Akt pathway.
Qiaozhuan Li,Ming Li,Ya Lan Wang,Nilufer Jasmine Selimah Fauzee,Yi Yang,Juan Pan,Lian Yang,Alexander J. Lazar +7 more
TL;DR: PARG knockdown, concomitant with inhibition of PARP, suppressed the metastatic potency of colon carcinoma cells by activation of PI3K/Akt signaling pathway.
Journal ArticleDOI
PAX3/7–FOXO1 fusion status in older rhabdomyosarcoma patient population by fluorescent in situ hybridization
TL;DR: Identification of a FOXO1 fusion appears to be an interesting tool for predicting outcomes in older rhabdomyosarcoma patients and is worth further investigations in this rare subgroup of RMS population.
Journal ArticleDOI
The International Collaboration for Cancer Classification and Research
Ian A. Cree,Iciar Indave,Jiri Zavadil,James McKay,Magali Olivier,Zisis Kozlakidis,Alexander J. Lazar,Chris Hyde,Stefan Holdenrieder,Ros Hastings,Nasir M. Rajpoot,Nasir M. Rajpoot,Nasir M. Rajpoot,Arnaud de la Fouchardiere,Brian Rous,Jean C. Zenklusen,Nicola Normanno,Richard L. Schilsky +17 more
TL;DR: The first IC3R meeting gathered representatives of major institutions involved in tumour classification and related fields to identify and discuss translational challenges in data comparability, standard setting, quality management, evidence evaluation and copyright, as well as to develop a collaborative plan for addressing these challenges.
Journal ArticleDOI
Diagnostic Value of TLE1 in Synovial Sarcoma: A Systematic Review and Meta-Analysis.
Marc El Beaino,Marc El Beaino,Daniel C. Jupiter,Tarek Assi,Elie El Rassy,Alexander J. Lazar,Dejka M. Araujo,Patrick P. Lin +7 more
TL;DR: TLE1 is a sensitive and specific marker for synovial sarcoma that can aid in its diagnosis and might have direct relevance to the pathophysiology of the disease.