A
Alexander J. Lazar
Researcher at University of Texas MD Anderson Cancer Center
Publications - 578
Citations - 55895
Alexander J. Lazar is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Sarcoma & Medicine. The author has an hindex of 93, co-authored 487 publications receiving 38717 citations. Previous affiliations of Alexander J. Lazar include Baylor College of Medicine & Beth Israel Deaconess Medical Center.
Papers
More filters
Journal ArticleDOI
CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study.
Chiara Colombo,Rosalba Miceli,Alexander J. Lazar,Federica Perrone,Raphael E. Pollock,Axel Le Cesne,Henk H. Hartgrink,Anne-Marie Cleton-Jansen,Julien Domont,Judith V.M.G. Bovée,Sylvie Bonvalot,Dina Lev,Alessandro Gronchi +12 more
TL;DR: The correlation between CTNNB1 mutation type and local recurrence in patients with primary, sporadic desmoid tumor (DT) is evaluated in this multi‐institutional, retrospective study.
Journal ArticleDOI
PanCancer insights from The Cancer Genome Atlas: the pathologist's perspective.
Lee Cooper,Lee Cooper,Elizabeth G. Demicco,Joel H. Saltz,Reid T. Powell,Arvind Rao,Alexander J. Lazar +6 more
TL;DR: Initial attempts to exploit TCGA imaging archives are document, some of the tools, and the rapidly evolving image analysis/feature extraction landscape are described, to inspire and challenge the pathology and cancer research communities to exploit these imaging resources.
Journal ArticleDOI
Sarcoma epidemiology and etiology: potential environmental and genetic factors.
TL;DR: Insight into the molecular basis of sarcoma inception, proliferation, and dissemination hopefully will lead to more effective therapies, and increased knowledge of the oncogenic mechanisms underlying sarcomagenesis is being generated.
Journal ArticleDOI
Adipophilin expression in sebaceous tumors and other cutaneous lesions with clear cell histology: an immunohistochemical study of 117 cases.
Daniel A. Ostler,Victor G. Prieto,Jon A. Reed,Michael T. Deavers,Alexander J. Lazar,Doina Ivan +5 more
TL;DR: Adipophilin expression is not as useful for the differential diagnosis that includes metastatic renal cell carcinoma, a rare but important, diagnostic differential and can be valuable in an immunohistochemical panel when evaluating cutaneous lesions with clear cell histology as it identifies intracytoplasmic lipid vesicles in sebaceous and xanthomatous lesions.
Journal ArticleDOI
Cutaneous Clear Cell Sarcoma: A Clinicopathologic, Immunohistochemical, and Molecular Analysis of 12 Cases Emphasizing its Distinction from Dermal Melanoma
Markus Hantschke,Thomas Mentzel,Arno Rütten,Gabriele Palmedo,Eduardo Calonje,Alexander J. Lazar,Heinz Kutzner +6 more
TL;DR: These 12 cases share an identical immunohistochemical profile with MM and thus can easily be confused with a dermal variant of spindle cell MM or metastasis of MM, and the specific translocation pattern was confirmed in all cases by fluorescence in situ hybridization.