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Alexandra C. Kendall

Researcher at University of Manchester

Publications -  31
Citations -  1004

Alexandra C. Kendall is an academic researcher from University of Manchester. The author has contributed to research in topics: Medicine & Inflammation. The author has an hindex of 16, co-authored 22 publications receiving 736 citations. Previous affiliations of Alexandra C. Kendall include Manchester Academic Health Science Centre & Royal Devon and Exeter Hospital.

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Bioactive lipid mediators in skin inflammation and immunity

TL;DR: This work focuses on psoriasis, atopic and contact dermatitis, acne vulgaris, wound healing and photodermatology that demonstrate dysregulation of bioactive lipid metabolism and examine ways of using this insight to inform novel therapeutics.
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Targeted lipidomic strategies for oxygenated metabolites of polyunsaturated fatty acids.

TL;DR: This review highlights current analytical approaches for a high-throughput lipidomic analysis of eicosanoids and related mediators in biological samples and facilitates research into their role in health and disease.
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Distribution of bioactive lipid mediators in human skin

TL;DR: The diversity of lipid mediators involved in maintaining tissue homeostasis in resting skin are demonstrated and hint at their contribution to signaling, cross-support, and functions of different skin compartments.
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Lipid functions in skin: Differential effects of n-3 polyunsaturated fatty acids on cutaneous ceramides, in a human skin organ culture model.

TL;DR: Dietary supplementation with EPA has the potential to alter the ceramide profile of the skin, and this may contribute to its anti-inflammatory profile, which has implications for formation of the epidermal lipid barrier, and signalling pathways within the skin mediated by ceramides and other sphingolipid species.