A
Alexandra C. Kendall
Researcher at University of Manchester
Publications - 31
Citations - 1004
Alexandra C. Kendall is an academic researcher from University of Manchester. The author has contributed to research in topics: Medicine & Inflammation. The author has an hindex of 16, co-authored 22 publications receiving 736 citations. Previous affiliations of Alexandra C. Kendall include Manchester Academic Health Science Centre & Royal Devon and Exeter Hospital.
Papers
More filters
Journal ArticleDOI
Bioactive lipid mediators in skin inflammation and immunity
TL;DR: This work focuses on psoriasis, atopic and contact dermatitis, acne vulgaris, wound healing and photodermatology that demonstrate dysregulation of bioactive lipid metabolism and examine ways of using this insight to inform novel therapeutics.
Journal ArticleDOI
Targeted lipidomic strategies for oxygenated metabolites of polyunsaturated fatty acids.
TL;DR: This review highlights current analytical approaches for a high-throughput lipidomic analysis of eicosanoids and related mediators in biological samples and facilitates research into their role in health and disease.
Journal ArticleDOI
Distribution of bioactive lipid mediators in human skin
Alexandra C. Kendall,Suzanne M. Pilkington,Karen A. Massey,Gary Sassano,Lesley E. Rhodes,Anna Nicolaou +5 more
TL;DR: The diversity of lipid mediators involved in maintaining tissue homeostasis in resting skin are demonstrated and hint at their contribution to signaling, cross-support, and functions of different skin compartments.
Journal ArticleDOI
Inflammatory Resolution Triggers a Prolonged Phase of Immune Suppression through COX-1/mPGES-1-Derived Prostaglandin E2
Justine Newson,Madhur P. Motwani,Alexandra C. Kendall,Anna Nicolaou,Giulio G. Muccioli,Mireille Alhouayek,Melanie Bennett,Rachel C van de Merwe,Sarah James,Roel P.H. De Maeyer,Derek W. Gilroy +10 more
TL;DR: A sequence of post-resolution events that dampens the propensity to develop autoimmune responses to endogenous antigens at the cost of local tissue infection is defined.
Journal ArticleDOI
Lipid functions in skin: Differential effects of n-3 polyunsaturated fatty acids on cutaneous ceramides, in a human skin organ culture model.
Alexandra C. Kendall,Magdalena Kiezel-Tsugunova,Luke C. Brownbridge,John L. Harwood,Anna Nicolaou +4 more
TL;DR: Dietary supplementation with EPA has the potential to alter the ceramide profile of the skin, and this may contribute to its anti-inflammatory profile, which has implications for formation of the epidermal lipid barrier, and signalling pathways within the skin mediated by ceramides and other sphingolipid species.