Alicia Amadoz

TL;DR: It is found that the response to death is largely tissue-specific and a model to predict time since death based on RNA data is developed, which is developed from the analysis of the transcriptome of a few readily accessible tissues.

TL;DR: Babelomics fifth release, which includes support for Next Generation Sequencing data including gene expression, exome or genome resequencing, is presented, which has simplified its interface, being now more intuitive.

TL;DR: A previously uncharacterized human lncRNA, CONCR (cohesion regulator noncoding RNA), is described that is transcriptionally activated by MYC and upregulated in multiple cancer types and reveals a direct role for an lnc RNA in the establishment of sister chromatid cohesion by modulating DDX11 enzymatic activity.

TL;DR: It is shown that it if fundamental to determine population- specific variant frequencies to distinguish real disease associations from population-specific polymorphisms, and also observed in variants that disrupt known drug binding sites.

TL;DR: A new method is proposed that models cell signaling using biological knowledge on signal transduction and recodes individual gene expression values into accurate measurements of changes in the activity of signaling circuits, which ultimately constitute high-throughput estimations of cell functionalities caused by gene activity within the pathway.