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Alison D. O'Brien
Researcher at Uniformed Services University of the Health Sciences
Publications - 195
Citations - 19269
Alison D. O'Brien is an academic researcher from Uniformed Services University of the Health Sciences. The author has contributed to research in topics: Escherichia coli & Shiga toxin. The author has an hindex of 73, co-authored 194 publications receiving 18602 citations. Previous affiliations of Alison D. O'Brien include Albert Einstein College of Medicine & Bristol Royal Infirmary.
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Journal ArticleDOI
Scale-up of transgenic tobacco cells that express intimin of enterohemorrhagic Escherichia coli O157:H7 for use as a transitional platform for an oral cattle vaccine
Kristin M. O’Neill,Kristin M. O’Neill,Anne M. Schilthuis,Calvin A. Leiter,Kurt M. Neihaus,Nicole A. Judge,Edda M. Twiddy,Alison D. O'Brien,Wayne R. Curtis +8 more
TL;DR: Plant tissue was transformed, produced in vitro, and available for feeding studies in a fraction of the time required to develop and grow transgenic plants.
Journal ArticleDOI
Certhrax Is an Antivirulence Factor for the Anthrax-Like Organism Bacillus cereus Strain G9241.
Yuliya I. Seldina,Courtney D. Petro,Stephanie L. Servetas,James M. Vergis,Christy L. Ventura,D. Scott Merrell,Alison D. O'Brien +6 more
TL;DR: Certhrax acts as an antivirulence factor in the anthrax-like organism B. cereus G9241, and is generated isogenic deletion mutations in the targeted toxin gene components and assessed the strains for virulence in high-susceptible (A/J) and moderately G 9241-sensitive (C57BL/6) mice.
Journal ArticleDOI
Erratum: Uncensored exchange of scientific results (Proceedings of the National Academy of Sciences (2003) 100, 4, (1464) DOI: 10.1073/pnas.0630491100)
Ronald M. Atlas,Philip Campbell,Nicholas R. Cozzarelli,Greg Curfman,Lynn W. Enquist,Gerald R. Fink,Annette Flanagin,Jacqueline Fletcher,Elizabeth George,Gordon G. Hammes,David Heyman,Thomas V. Inglesby,Samuel Kaplan,Donald Kennedy,Judith Krug,Rachel Levinson,Emilie A. Marcus,Henry Metzger,Stephen Morse,Alison D. O'Brien,Andrew B. Onderdonk,George Poste,Beatrice Renault,Robert Rich,Ariella M. Rosengard,Steven L. Salzberg,Mary Scanlan,Thomas Shenk,Herbert Tabor,Harold E. Varmus,Eckard Wimmer,Keith R. Yamamoto +31 more
Book ChapterDOI
Shiga and Shiga-Like Toxins: A Family of Related Cytotoxins
Alison D. O'Brien,Matthew P. Jackson,L. R. M. Marques,N. A. Strockbine,N. A. Strockbine,Debra L. Weinstein,M. A. Moore,Randall K. Holmes,John W. Newland,Roger Neill +9 more
TL;DR: The purpose of this report is to summarize the current understanding of the epidemiology, potential role in pathogenesis, structure, function and molecular genetics of the various members of the SLT family.