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Alison D. O'Brien
Researcher at Uniformed Services University of the Health Sciences
Publications - 195
Citations - 19269
Alison D. O'Brien is an academic researcher from Uniformed Services University of the Health Sciences. The author has contributed to research in topics: Escherichia coli & Shiga toxin. The author has an hindex of 73, co-authored 194 publications receiving 18602 citations. Previous affiliations of Alison D. O'Brien include Albert Einstein College of Medicine & Bristol Royal Infirmary.
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Flagella help Salmonella typhimurium survive within murine macrophages.
TL;DR: Results indicate that flagella either protect S. typhimurium from the intracellular killing mechanisms of murine macrophages or thatFlagella enhance the ability of S. Typhimurial to multiply within murine Macrophages.
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Cytotoxic necrotizing factor type 1-positive Escherichia coli causes increased inflammation and tissue damage to the prostate in a rat prostatitis model.
Karen E. Rippere-Lampe,Michael Lang,Howard Ceri,Merle E. Olson,Hank A. Lockman,Hank A. Lockman,Alison D. O'Brien +6 more
TL;DR: The results of this study provide the first demonstration of a role for any uropathogenic E.coli virulence factor in acute prostatitis and conclude that CNF1 contributes to E. coli virulence in a model of acute prost atitis.
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Growth of Escherichia coli in the presence of trimethoprim-sulfamethoxazole facilitates detection of Shiga-like toxin producing strains by colony blot assay
TL;DR: Subinhibitory concentrations of trimethoprim-sulfamethoxazole increased the total yield of Shiga-like toxin (SLT), produced by Shigella dysenteria 1 and by enterophathogenic and enterohemorrhagic strains of Escherichia coli.
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Investigation of enterohemorrhagic Escherichia coli O157:H7 adherence characteristics and invasion potential reveals a new attachment pattern shared by intestinal E. coli.
TL;DR: The log jam phenotype may represent a basal means by which E. coli bacteria attach to the human intestine.
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Overview and Historical Perspectives
James B. Kaper,Alison D. O'Brien +1 more
TL;DR: An overview of the history of Shiga toxin-producing Escherichia coli (STEC) in two phases is described and the basis for the review of current information regarding these fascinating and complex pathogens is provided.