A
Alison Vaughan
Researcher at University of Oxford
Publications - 24
Citations - 1217
Alison Vaughan is an academic researcher from University of Oxford. The author has contributed to research in topics: Nanopore sequencing & Plasmid. The author has an hindex of 10, co-authored 24 publications receiving 857 citations. Previous affiliations of Alison Vaughan include National Institute for Health Research & John Radcliffe Hospital.
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Journal ArticleDOI
Effects of control interventions on Clostridium difficile infection in England: an observational study
Kate E. Dingle,Kate E. Dingle,Kate E. Dingle,Xavier Didelot,T Phuong Quan,T Phuong Quan,T Phuong Quan,David W Eyre,David W Eyre,Nicole Stoesser,Nicole Stoesser,Tanya Golubchik,Tanya Golubchik,Rosalind M. Harding,Rosalind M. Harding,Daniel J. Wilson,Daniel J. Wilson,Daniel J. Wilson,David Griffiths,David Griffiths,Alison Vaughan,Alison Vaughan,John Finney,John Finney,David H. Wyllie,David H. Wyllie,David H. Wyllie,Sarah Oakley,Warren N. Fawley,Jane Freeman,K. Morris,Jessica Martin,Philip Howard,Sherwood L. Gorbach,Sherwood L. Gorbach,Ellie J. C. Goldstein,Diane M. Citron,Susan Hopkins,Susan Hopkins,Russell Hope,Alan P. Johnson,Alan P. Johnson,Mark H. Wilcox,Tim E. A. Peto,Tim E. A. Peto,Tim E. A. Peto,A. Sarah Walker,A. Sarah Walker,A. Sarah Walker,Derrick W. Crook,Derrick W. Crook,Derrick W. Crook,Carlos del Ojo Elias,Charles Crichton,Vasiliki Kostiou,Adam Giess,Jim Davies +56 more
TL;DR: Limiting fluoroquinolone prescribing appears to explain the decline in incidence of C difficile infections, above other measures, in Oxfordshire and Leeds, England.
Journal ArticleDOI
Nested Russian Doll-Like Genetic Mobility Drives Rapid Dissemination of the Carbapenem Resistance Gene blaKPC
Anna E. Sheppard,Nicole Stoesser,Daniel J. Wilson,Robert Sebra,Andrew Kasarskis,Luke Anson,Adam Giess,Louise Pankhurst,Alison Vaughan,Christopher J. Grim,Heather L. Cox,Anthony J. Yeh,Costi D. Sifri,A. Sarah Walker,Tim E. A. Peto,Derrick W. Crook,Amy J. Mathers +16 more
TL;DR: The findings demonstrate that nonclonal resistance gene dissemination can be extremely rapid, presenting significant challenges for public health surveillance and achieving effective control of antibiotic resistance.
Journal ArticleDOI
Relationship Between Bacterial Strain Type, Host Biomarkers, and Mortality in Clostridium difficile Infection
A. Sarah Walker,David W Eyre,David H. Wyllie,Kate E. Dingle,David Griffiths,Brian Shine,Sarah Oakley,Lily O’Connor,John Finney,Alison Vaughan,Derrick W. Crook,Mark H. Wilcox,Tim E. A. Peto +12 more
TL;DR: Clostridium difficile genotype predicts 14-day mortality in 1893 enzyme immunoassay–positive/culture-positive adults and correlates with genotype-specific changes in biomarkers, strongly implicating inflammatory pathways as a major influence on poor outcome.
Journal ArticleDOI
COVID-19: Rapid antigen detection for SARS-CoV-2 by lateral flow assay: A national systematic evaluation of sensitivity and specificity for mass-testing.
T Peto,Dominic Affron,Babak Afrough,Anita Agasu,Mark A. Ainsworth,Alison Allanson,Kate Allen,Collette Allen,Lorraine Archer,Natasha Ashbridge,Iman Aurfan,Miriam Avery,Ellena Badenoch,Priya Bagga,Rishab Balaji,Ella Baldwin,Sophie Barraclough,Carol Beane,John I. Bell,Tracy Benford,Susan Bird,Marina Bishop,Angela Bloss,Richard Body,Rosie Boulton,Abbie Bown,Carla Bratten,Chris Bridgeman,Dominic Britton,Tim Brooks,Margaret Broughton-Smith,Pauline Brown,Beverley Buck,Elaine Butcher,Wendy Byrne,Gloria Calderon,Siobhan Campbell,Olivia Carr,Penny Carter,Daniel P. Carter,Megan Cathrall,Matthew Catton,Jim Chadwick,David Chapman,Kevin K Chau,Tanzina Chaudary,Shaolin Chidavaenzi,Samatha Chilcott,Bea Choi,Hannah Claasen,Simon Clark,Richard Clarke,Dawn Clarke,Richard Clayton,Kayleigh Collins,Rima Colston,James Connolly,Eloïse Cook,Marie Corcoran,Ben Corley,Laura Costello,Caroline Coulson,Ant Crook,Derrick W. Crook,Silvia D'Arcangelo,Mary-Anne Darby,John Davis,Rosaline de Koning,Pauline Derbyshire,Pam Devall,Mark Dolman,Natalie Draper,Mark Driver,Sarah Dyas,Emily Eaton,Joy Edwards,Ruth Elderfield,Kate Ellis,Graham Ellis,Sue Elwell,Rachel Evans,Becky Evans,Marion Evans,Ranoromanana Evans,David W Eyre,Codie Fahey,Vanessa Fenech,Janet Field,Alice Field,Tom Foord,Tom Fowler,Mollie French,Hannah Fuchs,Jasmine Gan,Joseph Gernon,Geeta Ghadiali,Narindar Ghuman,Kerry Gibbons,Gurvinder Gill,Kate Gilmour,Anika Goel,Sally Gordon,Tillie Graham,Alexander Grassam-Rowe,David Green,Anna Gronert,Tegan Gumsley-Read,Claire Hall,Bassam Hallis,Sally Hammond,Peter Hammond,Beth Hanney,Victoria Hardy,Gabriella Harker,Andrew Harris,May Havinden-Williams,Elena Hazell,Joanne Henry,Kim Hicklin,Kelly Hollier,Ben Holloway,Sarah Hoosdally,Susan Hopkins,Lucy Hughes,Steve Hurdowar,Sally-Anne Hurford,Joanne Jackman,Harriet Jackson,Ruth Johns,Susan Johnston,Juliet Jones,Tinashe Kanyowa,Katie Keating-Fedders,Sharon Kempson,Iftikhar Khan,Beinn Khulusi,Thomas Knight,Anuradha Krishna,Patrick Lahert,Zoe Lampshire,Daniel Lasserson,Kirsten Lee,Lennard Y. W. Lee,Arabella Legard,Cristina Leggio,Justin Liu,T Lockett,Christopher H. Logue,Vanessa Lucas,Sheila F Lumley,Vindhya Maripuri,Des Markham,Emma Marshall,Philippa C Matthews,Sarah Mckee,Deborah F. McKee,Neil McLeod,Antoinette McNulty,Freddie Mellor,Rachel Michel,Alex Mighiu,Julie Miller,Zarina Mirza,Heena Mistry,Jane Mitchell,Mika Erik Moeser,Sophie Moore,Akhila Muthuswamy,Daniel Myers,Gemma Nanson,Mike Newbury,Scott Nicol,Harry Nuttall,Jewel Jones Nwanaforo,Louise Oliver,Wendy Osbourne,Jake Osbourne,Ashley Otter,Jodie Owen,Sulaksan Panchalingam,Dimitris Papoulidis,Juan Dobaldo Pavon,Arro Peace,Karen Pearson,Liam J Peck,Ashley Pegg,Suzannah Pegler,Helen Permain,Prem Perumal,Leon Peto,Tim E. A. Peto,Thanh Pham,H Pickford,Mark Pinkerton,Michelle Platton,Ashley Price,Emily A. Protheroe,Hellen Purnell,Lottie Rawden,Sara Read,Charles Reynard,Susan Ridge,Tom G. Ritter,James O. Robinson,Patrick Robinson,Gillian Rodger,Cathy Rowe,Bertie Rowell,Alexandra Rowlands,Sarah Sampson,Kathryn J Saunders,Rachel Sayers,Jackie Sears,Richard Sedgewick,Laura Seeney,Amanda Selassie,Lloyd Shail,Jane Shallcross,Lucy Sheppard,Anna Sherkat,Shelha Siddiqui,Alex Sienkiewicz,Lavanya Sinha,Jennifer Smith,Ella Smith,Emma Stanton,Thomas Starkey,Aleksander Stawiarski,Amelia Sterry,Joe Stevens,Mark Stockbridge,Nicole Stoesser,Anila Sukumaran,Angela Sweed,Sami Tatar,Hema Thomas,Carly Tibbins,Sian Tiley,Julie Timmins,Cara Tomas-Smith,Oliver Topping,Elena Turek,Toi Neibler,Kate Trigg-Hogarth,Elizabeth Truelove,Chris D. Turnbull,David Tyrrell,Alison Vaughan,John Vertannes,Richard Vipond,Linda Wagstaff,Joanne Waldron,Philip Walker,Ann Sarah Walker,Mary Walters,Jenny Wang,Ellie Watson,Kate Webberley,Kimerbley Webster,Grace Westland,Ian Wickens,Jane Willcocks,Herika Willis,Stephen W. Wilson,Barbara Wilson,Louise Woodhead,Deborah Wright,Bindhu Xavier,Fiona Yelnoorkar,Lisa Zeidan,Rangeni Zinyama +270 more
TL;DR: In this article, the authors evaluated the performance of Lateral flow device (LFD) immunoassays for SARS-CoV-2 infection and found that they have promising performance characteristics for mass population testing and can be used to identify infectious positive individuals.
Journal ArticleDOI
Maternal colonization with Streptococcus agalactiae and associated stillbirth and neonatal disease in coastal Kenya.
Anna C. Seale,Anna C. Seale,Angela C. Koech,Anna E. Sheppard,Hellen C. Barsosio,Joyce Langat,Emily Anyango,Stella Mwakio,Salim Mwarumba,Susan C. Morpeth,Susan C. Morpeth,Kirimi Anampiu,Alison Vaughan,Adam Giess,Polycarp Mogeni,Leahbell Walusuna,Hope Mwangudzah,Doris Mwanzui,Mariam Salim,Bryn Kemp,Bryn Kemp,Caroline Jones,Caroline Jones,Caroline Jones,Neema Mturi,Benjamin Tsofa,Edward Mumbo,David Mulewa,Victor Bandika,Musimbi Soita,Maureen Owiti,Norris Onzere,A. Sarah Walker,Stephanie J. Schrag,Stephen Kennedy,Greg Fegan,Greg Fegan,Derrick W. Crook,James A. Berkley,James A. Berkley +39 more
TL;DR: Maternal GBS colonization was less common in women with low socio-economic status, HIV infection and undernutrition, but when GBS-colonized, they were more probably colonized by the most virulent clone, CC17.