A
Alison W. Loren
Researcher at University of Pennsylvania
Publications - 196
Citations - 7431
Alison W. Loren is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 34, co-authored 167 publications receiving 5650 citations. Previous affiliations of Alison W. Loren include Children's Hospital of Philadelphia & Hospital of the University of Pennsylvania.
Papers
More filters
Journal ArticleDOI
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
David L. Porter,Wei-Ting Hwang,Noelle V. Frey,Simon F. Lacey,Pamela A. Shaw,Alison W. Loren,Adam Bagg,Katherine T. Marcucci,Angela Shen,Vanessa E. Gonzalez,David E Ambrose,Stephan A. Grupp,Anne Chew,Zhaohui Zheng,Michael C. Milone,Bruce L. Levine,J. Joseph Melenhorst,Carl H. June +17 more
TL;DR: The in vivo expansion of theCAR T cells correlated with clinical responses, and the CAR T cells persisted and remained functional beyond 4 years in the first two patients achieving CR, suggesting that disease eradication may be possible in some patients with advanced CLL.
Journal ArticleDOI
Fertility Preservation in Patients With Cancer: ASCO Clinical Practice Guideline Update.
Kutluk Oktay,Brittany E. Harvey,Ann H. Partridge,Gwendolyn P. Quinn,Joyce Reinecke,Hugh S. Taylor,W. Hamish B. Wallace,Erica T. Wang,Alison W. Loren +8 more
TL;DR: There is conflicting evidence to recommend gonadotrophin-releasing hormone agonists (GnRHa) and other means of ovarian suppression for fertility preservation and the panel notes that the field of ovarian tissue cryopreservation is advancing quickly and may evolve to become standard therapy in the future.
Journal ArticleDOI
Increasing Incidence of Chronic Graft-versus-Host Disease in Allogeneic Transplantation: A Report from the Center for International Blood and Marrow Transplant Research
Sally Arai,Mukta Arora,Tao Wang,Tao Wang,Stephen R. Spellman,Wensheng He,Daniel R. Couriel,Alvaro Urbano-Ispizua,Corey Cutler,Andrea Bacigalupo,Minoo Battiwalla,Mary E.D. Flowers,Mark B. Juckett,Stephanie J. Lee,Alison W. Loren,Thomas R. Klumpp,Susan E. Prockup,Olle Ringdén,Bipin N. Savani,Gérard Socié,Kirk R. Schultz,Thomas R. Spitzer,Takanori Teshima,Christopher Bredeson,David A. Jacobsohn,Robert J. Hayashi,William R. Drobyski,Haydar Frangoul,Gorgun Akpek,Vincent T. Ho,Victor Lewis,Robert Peter Gale,John Koreth,Nelson J. Chao,Mahmoud Aljurf,Brenda W. Cooper,Mary J. Laughlin,Jack W. Hsu,Peiman Hematti,Leo F. Verdonck,Melhelm M. Solh,Maxim Norkin,Vijay Reddy,Rodrigo Martino,Shahinaz M. Gadalla,Jenna D. Goldberg,Philip L. McCarthy,José A. Pérez-Simón,Nandita Khera,Ian D. Lewis,Yoshiko Atsuta,Richard F. Olsson,Richard F. Olsson,Wael Saber,Edmund K. Waller,Didier Blaise,Joseph Pidala,Paul J. Martin,Prakash Satwani,Martin Bornhäuser,Yoshihiro Inamoto,Daniel J. Weisdorf,Mary M. Horowitz,Steven Z. Pavletic +63 more
TL;DR: In patients with cGVHD, nonrelapse mortality has decreased over time, but at 5 years there were no significant differences among different time periods and the mounting need for addressing this major late complication of transplantation in future research is underscores.
Journal ArticleDOI
Post-transplant lymphoproliferative disorder: a review.
TL;DR: Immune-based therapies such as monoclonal anti-B-cell antibodies, interferon-α, and EBV-specific donor T cells, either as treatment for PTLD or as prophylaxis in high-risk patients, represent promising new directions in the treatment of this disease.
Journal ArticleDOI
Association of Racial/Ethnic and Gender Concordance Between Patients and Physicians With Patient Experience Ratings.
Junko Takeshita,Shiyu Wang,Alison W. Loren,Nandita Mitra,Justine Shults,Daniel B. Shin,Deirdre Sawinski +6 more
TL;DR: Higher Press Ganey survey scores were associated with racial/ethnic concordance between patients and their physicians; thus, efforts to improve the patient experience among racially/ethnically discordant patient-physician dyads may be necessary to improve health care delivery.