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Gorgun Akpek
Researcher at Rush University Medical Center
Publications - 92
Citations - 3628
Gorgun Akpek is an academic researcher from Rush University Medical Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 31, co-authored 91 publications receiving 3157 citations. Previous affiliations of Gorgun Akpek include University of Maryland Marlene and Stewart Greenebaum Cancer Center & Johns Hopkins University.
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Journal ArticleDOI
Dose-intensive melphalan with blood stem-cell support for the treatment of AL (amyloid light-chain) amyloidosis : Survival and responses in 25 patients
Raymond L. Comenzo,Evan Vosburgh,Rodney H. Falk,Vaishali Sanchorawala,Johann Reisinger,Simon W Dubrey,Laura M. Dember,John L. Berk,Gorgun Akpek,Michael P. LaValley,Carl O'Hara,Charles F. Arkin,Daniel G. Wright,Martha Skinner +13 more
TL;DR: Dose-intensive therapy should currently be considered as the preferred therapy for patients with AL amyloidosis who meet functional criteria for autologous transplantation, and the improvement in the median performance status of the 17 survivors at follow-up is statistically significant versus baseline.
Journal ArticleDOI
Increasing Incidence of Chronic Graft-versus-Host Disease in Allogeneic Transplantation: A Report from the Center for International Blood and Marrow Transplant Research
Sally Arai,Mukta Arora,Tao Wang,Tao Wang,Stephen R. Spellman,Wensheng He,Daniel R. Couriel,Alvaro Urbano-Ispizua,Corey Cutler,Andrea Bacigalupo,Minoo Battiwalla,Mary E.D. Flowers,Mark B. Juckett,Stephanie J. Lee,Alison W. Loren,Thomas R. Klumpp,Susan E. Prockup,Olle Ringdén,Bipin N. Savani,Gérard Socié,Kirk R. Schultz,Thomas R. Spitzer,Takanori Teshima,Christopher Bredeson,David A. Jacobsohn,Robert J. Hayashi,William R. Drobyski,Haydar Frangoul,Gorgun Akpek,Vincent T. Ho,Victor Lewis,Robert Peter Gale,John Koreth,Nelson J. Chao,Mahmoud Aljurf,Brenda W. Cooper,Mary J. Laughlin,Jack W. Hsu,Peiman Hematti,Leo F. Verdonck,Melhelm M. Solh,Maxim Norkin,Vijay Reddy,Rodrigo Martino,Shahinaz M. Gadalla,Jenna D. Goldberg,Philip L. McCarthy,José A. Pérez-Simón,Nandita Khera,Ian D. Lewis,Yoshiko Atsuta,Richard F. Olsson,Richard F. Olsson,Wael Saber,Edmund K. Waller,Didier Blaise,Joseph Pidala,Paul J. Martin,Prakash Satwani,Martin Bornhäuser,Yoshihiro Inamoto,Daniel J. Weisdorf,Mary M. Horowitz,Steven Z. Pavletic +63 more
TL;DR: In patients with cGVHD, nonrelapse mortality has decreased over time, but at 5 years there were no significant differences among different time periods and the mounting need for addressing this major late complication of transplantation in future research is underscores.
Journal ArticleDOI
Development of a prognostic model for grading chronic graft-versus-host disease.
Gorgun Akpek,Marianna Zahurak,Steven Piantadosi,Jeffrey H. Margolis,Jon Doherty,Robert K. Davidson,Georgia B. Vogelsang +6 more
TL;DR: These prognostic models might be useful in grouping the patients with similar outcome and to form a basis for a new grading of cGVHD.
Journal ArticleDOI
Combination immunotherapy using adoptive T-cell transfer and tumor antigen vaccination on the basis of hTERT and survivin after ASCT for myeloma
Aaron P. Rapoport,Nicole A. Aqui,Edward A. Stadtmauer,Dan T. Vogl,Hong-Bin Fang,Ling Cai,Stephen Janofsky,Anne Chew,Jan Storek,Gorgun Akpek,Ashraf Badros,Saul Yanovich,Ming Tan,Elizabeth Veloso,Marcela F. Pasetti,Alan S. Cross,Alan S. Cross,Sunita Philip,Heather Murphy,Rita Bhagat,Zhaohui Zheng,Todd Milliron,Julio Cotte,Andrea Cannon,Bruce L. Levine,Robert H. Vonderheide,Carl H. June +26 more
TL;DR: Adoptive transfer of tumor antigen vaccine-primed and costimulated T cells leads to augmented and accelerated cellular and humoral immune reconstitution, including antitumor immunity, after autologous stem cell transplantation for myeloma.
Journal ArticleDOI
Long-Term Results of Blood and Marrow Transplantation for Hodgkin’s Lymphoma
Gorgun Akpek,Richard F. Ambinder,Steven Piantadosi,Ross A. Abrams,Robert A. Brodsky,Georgia B. Vogelsang,Marianna Zahurak,D. J. Fuller,Carole B. Miller,Stephen J. Noga,Ephraim J. Fuchs,Ian W. Flinn,Paul O'Donnell,Eric J. Seifter,Risa B. Mann,Richard J. Jones +15 more
TL;DR: There seems to be a clinical graft-versus-HL effect associated with allo BMT, which seems to have a lower risk of secondary AML/MDS than auto BMT and warrants continued study in HL.