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Alistair R. R. Forrest
Researcher at Harry Perkins Institute of Medical Research
Publications - 184
Citations - 27204
Alistair R. R. Forrest is an academic researcher from Harry Perkins Institute of Medical Research. The author has contributed to research in topics: Gene & Regulation of gene expression. The author has an hindex of 59, co-authored 175 publications receiving 23544 citations. Previous affiliations of Alistair R. R. Forrest include Griffith University & Centre for Life.
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Journal ArticleDOI
Expression analysis of the long non-coding RNA antisense to Uchl1 (AS Uchl1) during dopaminergic cells' differentiation in vitro and in neurochemical models of Parkinson's disease.
Claudia Carrieri,Alistair R. R. Forrest,Claudio Santoro,Francesca Persichetti,Piero Carninci,Silvia Zucchelli,Stefano Gustincich +6 more
TL;DR: It is shown that AS Uchl1 expression is under the regulation of Nurr1, a major transcription factor involved in dopaminergic cells' differentiation and maintenance, extending the understanding on the role of antisense transcription in the brain.
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Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation
Hiromasa Morikawa,Naganari Ohkura,Alexis Vandenbon,Masayoshi Itoh,Sayaka Nagao-Sato,Hideya Kawaji,Timo Lassmann,Piero Carninci,Yoshihide Hayashizaki,Alistair R. R. Forrest,Daron M. Standley,Hiroshi Date,Shimon Sakaguchi +12 more
TL;DR: It is found that Treg-specific DNA hypomethylated regions were closely associated with Treg up-regulated transcriptional start site clusters, whereas Foxp3 binding regions had no significant correlation with either up- or down-regulated clusters in nonactivated Treg cells.
Journal Article
Generation of diversity in the innate immune system: Macrophage heterogeneity arises from gene-autonomous transcriptional probability of individual inducible genes (vol 168, pg 44, 2002)
Timothy Ravasi,Christine A. Wells,Alistair R. R. Forrest,N Walsh,David M. Underhill,Brandon J. Wainwright,Alan Aderem,Sean M. Grimmond,David A. Hume +8 more
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Predicting cell-to-cell communication networks using NATMI
TL;DR: Analysis of the Tabula Muris (organism-wide) atlas confirms the previous prediction that autocrine signalling is a major feature of cell-to-cell communication networks, while also revealing that hundreds of ligands and their cognate receptors are co-expressed in individual cells suggesting a substantial potential for self-signalling.
Journal ArticleDOI
A rescue strategy for multimapping short sequence tags refines surveys of transcriptional activity by CAGE
Geoffrey J. Faulkner,Alistair R. R. Forrest,Alistair M. Chalk,Kate Schroder,Yoshihide Hayashizaki,Piero Carninci,David A. Hume,Sean M. Grimmond +7 more
TL;DR: The results suggest that the multimap tags produced by high-throughput, short sequence tag-based approaches can be rescued to augment greatly the transcriptome coverage provided by single-map tags alone.