A
Alistair R. R. Forrest
Researcher at Harry Perkins Institute of Medical Research
Publications - 184
Citations - 27204
Alistair R. R. Forrest is an academic researcher from Harry Perkins Institute of Medical Research. The author has contributed to research in topics: Gene & Regulation of gene expression. The author has an hindex of 59, co-authored 175 publications receiving 23544 citations. Previous affiliations of Alistair R. R. Forrest include Griffith University & Centre for Life.
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On-the-fly selection of cell-specific enhancers, genes, miRNAs and proteins across the human body using SlideBase.
Hans Ienasescu,Kang Li,Robin Andersson,Morana Vitezic,Sarah Rennie,Yun Chen,Kristoffer Vitting-Seerup,Emil Lagoni,Mette Boyd,Jette Bornholdt,Michiel J. L. de Hoon,Hideya Kawaji,Timo Lassmann,Yoshihide Hayashizaki,Alistair R. R. Forrest,Piero Carninci,Albin Sandelin +16 more
TL;DR: SlideBase is a web tool which offers a new way of selecting genes, promoters, enhancers and microRNAs that are preferentially expressed/used in a specified set of cells/tissues, based on the use of interactive sliders.
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Integration of genetics and miRNA-target gene network identified disease biology implicated in tissue specificity.
Saori Sakaue,Saori Sakaue,Jun Hirata,Yuichi Maeda,Yuichi Maeda,Eiryo Kawakami,Takuro Nii,Takuro Nii,Toshihiro Kishikawa,Kazuyoshi Ishigaki,Chikashi Terao,Ken Suzuki,Masato Akiyama,Naomasa Suita,Tatsuo Masuda,Kotaro Ogawa,Kenichi Yamamoto,Yukihiko Saeki,Masato Matsushita,M. Yoshimura,Hidetoshi Matsuoka,Katsunori Ikari,Atsuo Taniguchi,Hisashi Yamanaka,Hideya Kawaji,Timo Lassmann,Masayoshi Itoh,Hiroyuki Yoshitomi,Hiromu Ito,Koichiro Ohmura,Alistair R. R. Forrest,Yoshihide Hayashizaki,Piero Carninci,Atsushi Kumanogoh,Yoichiro Kamatani,Michiel J. L. de Hoon,Kazuhiko Yamamoto,Yukinori Okada +37 more
TL;DR: This work expands a previous method to quantitatively evaluate enrichment of genome-wide association study (GWAS) signals on miRNA–target gene networks (MIGWAS) to further estimate tissue-specific enrichment, and highlighted that miRNA-target gene network contributes to human disease genetics in a cell type-specific manner.
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Systematic analysis of transcription start sites in avian development.
Marina Lizio,Ruslan Deviatiiarov,Hiroki Nagai,Laura Galan,Erik Arner,Masayoshi Itoh,Timo Lassmann,Takeya Kasukawa,Akira Hasegawa,Marian A. Ros,Yoshihide Hayashizaki,Piero Carninci,Alistair R. R. Forrest,Hideya Kawaji,Oleg Gusev,Guojun Sheng +15 more
TL;DR: This work provides evidence that precise TSS mapping in combination with Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-on technology enables us, for the first time, to efficiently target endogenous avian genes for transcriptional activation.
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Transcriptional profiling of the human fibrillin/LTBP gene family, key regulators of mesenchymal cell functions
Margaret R. Davis,Robin Andersson,Jessica Severin,Michiel J. L. de Hoon,Nicolas Bertin,J Kenneth Baillie,Hideya Kawaji,Albin Sandelin,Alistair R. R. Forrest,Kim M. Summers,Kim M. Summers +10 more
TL;DR: This study highlights the role of alternative transcription start sites in regulating the tissue specificity of closely related genes and suggests that this important class of extracellular matrix proteins is subject to subtle regulatory variations that explain the differential roles of members of this gene family.
Journal ArticleDOI
New era in genetics of early-onset muscle disease: Breakthroughs and challenges
TL;DR: In this review, the recent advances made and the challenges ahead for the molecular diagnosis of early-onset muscle diseases are highlighted.