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Allen Grolla
Researcher at Public Health Agency of Canada
Publications - 60
Citations - 6431
Allen Grolla is an academic researcher from Public Health Agency of Canada. The author has contributed to research in topics: Ebola virus & Marburg virus disease. The author has an hindex of 30, co-authored 56 publications receiving 5992 citations.
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Journal ArticleDOI
The Genome Sequence of the SARS-associated Coronavirus
Marco A. Marra,Steven J.M. Jones,Caroline R. Astell,Robert A. Holt,Angela Brooks-Wilson,Yaron S.N. Butterfield,Jaswinder Khattra,Jennifer Asano,Sarah Barber,Susanna Y. Chan,Alison Cloutier,Shaun M. Coughlin,Doug Freeman,Noreen Girn,Obi L. Griffith,Stephen Leach,Michael Mayo,Helen McDonald,Stephen B. Montgomery,Pawan Pandoh,Anca Petrescu,A. Gordon Robertson,Jacqueline E. Schein,Asim Siddiqui,Duane E. Smailus,Jeff M. Stott,George S. Yang,Francis A. Plummer,Anton Andonov,Harvey Artsob,Nathalie Bastien,Kathy Bernard,Timothy F. Booth,Donnie Bowness,Martin Czub,Michael Drebot,Lisa Fernando,Ramon Flick,Michael Garbutt,Michael Gray,Allen Grolla,Steven M. Jones,Heinz Feldmann,Adrienne Meyers,Amin Kabani,Yan Li,Susan Normand,Ute Ströher,Graham A. Tipples,Shaun Tyler,Robert Vogrig,Diane M. Ward,Brynn Watson,Robert C. Brunham,Mel Krajden,Martin Petric,Danuta M. Skowronski,Chris Upton,Rachel L. Roper +58 more
TL;DR: The genome sequence reveals that the severe acute respiratory syndrome–associated coronavirus known as the Tor2 isolate is only moderately related to other known coronaviruses, andylogenetic analysis of the predicted viral proteins indicates that the virus does not closely resemble any of the three previously known groups of coronavirs.
Journal ArticleDOI
Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses.
Steven Jones,Heinz Feldmann,Heinz Feldmann,Ute Ströher,Ute Ströher,Joan B. Geisbert,Lisa Fernando,Allen Grolla,Hans-Dieter Klenk,Nancy J. Sullivan,Viktor E. Volchkov,Elizabeth A. Fritz,Kathleen M. Daddario,Lisa E. Hensley,Peter B. Jahrling,Thomas W. Geisbert +15 more
TL;DR: The data suggest that these replication-competent vaccines against EBOV and MARV based on attenuated recombinant vesicular stomatitis virus vectors are safe and highly efficacious in a relevant animal model.
Journal ArticleDOI
Person-to-Person Transmission of Nipah Virus in a Bangladeshi Community
Emily S. Gurley,Joel M. Montgomery,M. Jahangir Hossain,Michael Bell,Abul Kalam al Azad,M. R. Islam,Mohammed Abdur Rahim Molla,Darin S. Carroll,Thomas G. Ksiazek,Paul A. Rota,Luis Lowe,James A. Comer,Pierre E. Rollin,Markus Czub,Markus Czub,Allen Grolla,Heinz Feldmann,Heinz Feldmann,Stephen P. Luby,Stephen P. Luby,Jennifer L. Woodward,Robert F. Breiman,Robert F. Breiman +22 more
TL;DR: Transmission of this virus highlights the need for infection control strategies for resource-poor settings and calls for increased awareness of infection control measures in these settings.
Journal ArticleDOI
Panmicrobial oligonucleotide array for diagnosis of infectious diseases.
Gustavo Palacios,Phuong-Lan Quan,Omar Jabado,Sean Conlan,David L. Hirschberg,Yang Liu,Junhui Zhai,Neil Renwick,Jeffrey Hui,Hedi Hegyi,Hedi Hegyi,Allen Grolla,James E. Strong,Jonathan S. Towner,Thomas W. Geisbert,Peter B. Jahrling,Cornelia Büchen-Osmond,Heinz Ellerbrok,María Paz Sánchez-Seco,Yves A. Lussier,Pierre Formenty,Stuart T. Nichol,Heinz Feldmann,Heinz Feldmann,Thomas Briese,W. Ian Lipkin +25 more
TL;DR: GreeneChipPm, a panmicrobial microarray comprising 29,455 sixty-mer oligonucleotide probes for vertebrate viruses, bacteria, fungi, and parasites, confirmed the presence of viruses and bacteria identified by other methods, and implicated Plasmodium falciparum in an unexplained fatal case of hemorrhagic feverlike disease during the Marburg hemorrhagic Fever outbreak in Angola in 2004–2005.
Journal ArticleDOI
Effective post-exposure treatment of Ebola infection.
Heinz Feldmann,Steven M. Jones,Steven M. Jones,Kathleen M. Daddario-DiCaprio,Kathleen M. Daddario-DiCaprio,Joan B. Geisbert,Ute Ströher,Ute Ströher,Allen Grolla,Mike Bray,Elizabeth A. Fritz,Lisa Fernando,Friederike Feldmann,Lisa E. Hensley,Thomas W. Geisbert,Thomas W. Geisbert +15 more
TL;DR: It is shown that a single injection of a live-attenuated recombinant vesicular stomatitis virus vector expressing the Ebola virus glycoprotein completely protected rodents and nonhuman primates from lethal Ebola challenge.