James E. Strong

TL;DR: SARS-CoV-2 Vero cell infectivity was only observed for RT-PCR Ct < 24 and STT < 8 days, suggesting Infectivity of patients with Ct >24 and duration of symptoms >8 days may be low.

TL;DR: It is shown that a combination of monoclonal antibodies (ZMapp), optimized from two previous antibody cocktails, is able to rescue 100% of rhesus macaques when treatment is initiated up to 5 days post-challenge, and ZMapp exceeds the efficacy of any other therapeutics described so far.

TL;DR: GreeneChipPm, a panmicrobial microarray comprising 29,455 sixty-mer oligonucleotide probes for vertebrate viruses, bacteria, fungi, and parasites, confirmed the presence of viruses and bacteria identified by other methods, and implicated Plasmodium falciparum in an unexplained fatal case of hemorrhagic feverlike disease during the Marburg hemorrhagic Fever outbreak in Angola in 2004–2005.

TL;DR: There is an urgent need to better understand the ecology of Ebola virus in nature with the increasing frequency of human filovirus outbreaks and the tremendous impact of infection on the already threatened great ape populations.

TL;DR: Compared pathology and global gene expression profiles in bronchial tissue from macaques infected with either the reconstructed 1918 pandemic virus or the highly pathogenic avian H5N1 virus A/Vietnam/1203/04 suggest that the severity of disease in 1918 virus-infected macaques is a consequence of the early up-regulation of cell death and inflammatory related genes, in which additive or synergistic effects likely dictate the severityof tissue damage.