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Alp Usubutun
Researcher at Hacettepe University
Publications - 133
Citations - 4539
Alp Usubutun is an academic researcher from Hacettepe University. The author has contributed to research in topics: Metastasis & Endometrial cancer. The author has an hindex of 23, co-authored 125 publications receiving 3989 citations.
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Journal ArticleDOI
Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide study
Silvia de Sanjosé,Wim Quint,Laia Alemany,D.T. Geraets,Jo Ellen Klaustermeier,Belen Lloveras,Sara Tous,Ana Félix,Luis Eduardo Bravo,Hai Rim Shin,Carlos S. Vallejos,Patricia Alonso de Ruiz,Marcus Aurelho Lima,Núria Guimerà,Omar Clavero,Maria Alejo,Antonio Llombart-Bosch,Chou Cheng-Yang,Silvio Tatti,Elena Kasamatsu,Ermina Iljazovic,Michael Odida,Rodrigo Prado,Muhieddine Seoud,Magdalena Grce,Alp Usubutun,Asha Jain,Gustavo Adolfo Hernandez Suarez,Luis Estuardo Lombardi,Aekunbiola Banjo,Clara Menendez,Efren J. Domingo,Julio Velasco,Ashrafun Nessa,Saibua Chichareon,You-Lin Qiao,Enrique Lerma,Suzanne M. Garland,Toshiyuki Sasagawa,Annabelle Ferrera,Doudja Hammouda,Luciano Mariani,Adela Pelayo,Ivo Šteiner,Esther Oliva,Chris J. L. M. Meijer,Waleed Al-Jassar,Eugenia Cruz,Thomas C. Wright,Ana Puras,Cecilia L. Llave,Maria Tzardi,Theodoros Agorastos,Victoria Garcia-Barriola,Christine Clavel,Jaume Ordi,Miguel Andújar,Xavier Castellsagué,Gloria I. Sanchez,Andrzej Nowakowski,Jacob Bornstein,Nubia Muñoz,F. Xavier Bosch +62 more
TL;DR: HPV types 16, 18, 31, 33, 35, 45, 52, and 58 should be given priority when the cross-protective effects of current vaccines are assessed, and for formulation of recommendations for the use of second-generation polyvalent HPV vaccines, according to this largest assessment of HPV genotypes to date.
Journal ArticleDOI
Worldwide human papillomavirus genotype attribution in over 2000 cases of intraepithelial and invasive lesions of the vulva
Silvia de Sanjosé,Laia Alemany,Jaume Ordi,Sara Tous,Maria Alejo,Susan M. Bigby,Elmar A. Joura,Paula Maldonado,Jan Laco,Ignacio G. Bravo,August Vidal,Núria Guimerà,Paul Cross,Gerard Wain,Karl Ulrich Petry,Luciano Mariani,Christine Bergeron,Václav Mandys,Adela Rosa Sica,Ana Félix,Alp Usubutun,Muhieddine Seoud,Gustavo Hernández-Suárez,Andrzej Nowakowski,G. Wilson,Véronique Dalstein,Monika Hampl,Elena Kasamatsu,Luis Estuardo Lombardi,Leopoldo Tinoco,Isabel Alvarado-Cabrero,Myriam Perrotta,Neerja Bhatla,Theodoros Agorastos,Charles F. Lynch,Marc T. Goodman,Hai Rim Shin,Halina Viarheichyk,Robert Jach,M. O.L.Eugenia Cruz,Julio Velasco,Carla Molina,Jacob Bornstein,Annabelle Ferrera,Efren J. Domingo,Cheng Yang Chou,Adekunbiola Aina Fehintola Banjo,Xavier Castellsagué,Michael Pawlita,Belen Lloveras,Wim Quint,Nubia Muñoz,F. Xavier Bosch +52 more
TL;DR: Combined data from HPV-DNA and p16(INK4a) testing are likely to represent a closer estimate of the real fraction of IVC induced by HPV, indicating that HPV contribution in invasive vulvar cancer has probably been overestimated.
Journal ArticleDOI
The protective effect of taurine against gentamicin‐induced acute tubular necrosis in rats
Ayşen Erdem,Nimet Ünay Gündogan,Alp Usubutun,Kamer Kilinc,S. Remzi Erdem,Aysun Kara,Atilla Bozkurt +6 more
TL;DR: It is suggested that taurine treatment attenuates the accumulation of gentamicin within kidney tissue and counteracts the deleterious effect of Gentamicin on renal tubular function.
Journal ArticleDOI
Activation of the canonical Wnt pathway during genital keratinocyte transformation: a model for cervical cancer progression.
Aykut Üren,Shannon Fallen,Hang Yuan,Alp Usubutun,Türkan Küçükali,Richard Schlegel,Jeffrey A. Toretsky +6 more
TL;DR: The results suggest that the transformation of HPV expressing human keratinocytes requires activation of the Wnt pathway and that this activation may serve as a screening tool in HPV-positive populations to detect malignant progression.
Journal Article
Evaluation of 36 patients from Turkey with neuronal ceroid lipofuscinosis: clinical, neurophysiological, neuroradiological and histopathologic studies.
Meral Topçu,Hüseyin Tan,Dilek Yalnizoglu,Alp Usubutun,Isil Saatci,Müjgan Aynaci,Banu Anlar,Haluk Topaloglu,Güzide Turanli,Gülşen Köse,Sabiha Aysun +10 more
TL;DR: Clinical picture of NCL in advanced stages of the disease was similar regardless of the subtype, and images of brainstem involvement, especially pons, and cerebellar atrophy in patients with Turkish variant showed a slower course compared to late infantile NCL.