Amanda F. Bolgioni

TL;DR: Cyfip2 was identified as a major significant genetic factor underlying binge eating and provided a behavioral paradigm for future genome-wide association studies in populations with increased genetic complexity.

TL;DR: Analysis of evidence that implicates core components of the Hippo tumor suppressor pathway as having key roles in both the direct and indirect regulation of centrosome number suggests that in addition to acquiring extra centrosomes, cancer cells must also adapt to overcome the deleterious consequences associated with them.

TL;DR: A comprehensive gain-of-function genome-wide screen to identify microRNAs (miRNAs) that are sufficient to promote the proliferation of tetraploid cells reveals several avenues through which tetraPloid cells may regain the proliferative capacity necessary to drive tumorigenesis.

TL;DR: In this article, the authors investigated the impact of additional complementary training activities on the time to degree or diminished research productivity of doctoral students at 10 National Institutes of Health (NIH) awardee institutions, including career panels, skill-building workshops, job search workshops, site visits and internships.

TL;DR: Live-cell imaging protocols to assess cell fate decisions following treatment with the anti-mitotic drug paclitaxel are described and methods to visualize whether mitotically arrested cells die directly from mitosis or slip back into interphase are demonstrated.