A
Amanda J. Martinot
Researcher at Tufts University
Publications - 18
Citations - 1314
Amanda J. Martinot is an academic researcher from Tufts University. The author has contributed to research in topics: Vaccination & Immune system. The author has an hindex of 6, co-authored 18 publications receiving 798 citations. Previous affiliations of Amanda J. Martinot include Beth Israel Deaconess Medical Center.
Papers
More filters
Journal ArticleDOI
SARS-CoV-2 infection protects against rechallenge in rhesus macaques.
Abishek Chandrashekar,Jinyan Liu,Amanda J. Martinot,Amanda J. Martinot,Katherine McMahan,Noe B. Mercado,Lauren Peter,Lisa H. Tostanoski,Jingyou Yu,Zoltan Maliga,Michael Nekorchuk,Kathleen Busman-Sahay,Margaret Terry,Linda M. Wrijil,Sarah Ducat,David R. Martinez,Caroline Atyeo,Caroline Atyeo,Stephanie Fischinger,John S. Burke,Matthew D. Slein,Laurent Pessaint,Alex Van Ry,Jack Greenhouse,Tammy Taylor,Kelvin Blade,Anthony Cook,Brad Finneyfrock,Renita Brown,Elyse Teow,Jason Velasco,Roland Zahn,Frank Wegmann,Peter Abbink,Esther A. Bondzie,Gabriel Dagotto,Gabriel Dagotto,Makda S. Gebre,Makda S. Gebre,Xuan He,Catherine Jacob-Dolan,Catherine Jacob-Dolan,Nicole Kordana,Zhenfeng Li,Michelle A. Lifton,Shant H. Mahrokhian,Lori F. Maxfield,Ramya Nityanandam,Joseph P. Nkolola,Aaron G. Schmidt,Andrew D. Miller,Ralph S. Baric,Galit Alter,Peter K. Sorger,Jacob D. Estes,Hanne Andersen,Mark G. Lewis,Dan H. Barouch,Dan H. Barouch +58 more
TL;DR: Data show that SARS-CoV-2 infection induced protective immunity against reexposure in nonhuman primates, and these findings have key implications for public health and economic initiatives if validated in human studies.
Journal ArticleDOI
Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters.
Lisa H. Tostanoski,Frank Wegmann,Amanda J. Martinot,Amanda J. Martinot,Carolin Loos,Carolin Loos,Katherine McMahan,Noe B. Mercado,Jingyou Yu,Chi N. Chan,Stephen Bondoc,Carly E. Starke,Michael Nekorchuk,Kathleen Busman-Sahay,Cesar Piedra-Mora,Cesar Piedra-Mora,Linda M. Wrijil,Sarah Ducat,Jerome Custers,Caroline Atyeo,Caroline Atyeo,Stephanie Fischinger,Stephanie Fischinger,John S. Burke,Jared Feldman,Jared Feldman,Blake M. Hauser,Blake M. Hauser,Timothy M. Caradonna,Timothy M. Caradonna,Esther A. Bondzie,Gabriel Dagotto,Gabriel Dagotto,Makda S. Gebre,Makda S. Gebre,Catherine Jacob-Dolan,Catherine Jacob-Dolan,Zijin Lin,Shant H. Mahrokhian,Felix Nampanya,Ramya Nityanandam,Laurent Pessaint,Maciel Porto,Vaneesha Ali,Dalia Benetiene,Komlan Tevi,Hanne Leth Andersen,Mark G. Lewis,Aaron G. Schmidt,Aaron G. Schmidt,Douglas A. Lauffenburger,Galit Alter,Jacob D. Estes,Hanneke Schuitemaker,Roland Zahn,Dan H. Barouch +55 more
TL;DR: It is shown that high-dose intranasal SARS-CoV-2 infection in hamsters results in severe clinical disease, including high levels of virus replication in tissues, extensive pneumonia, weight loss and mortality in a subset of animals.
Journal ArticleDOI
Optimization of Non-Coding Regions for a Non-Modified mRNA COVID-19 Vaccine.
Makda S. Gebre,Susanne Rauch,Nicole Roth,Jingyou Yu,Abishek Chandrashekar,Noe B. Mercado,Xuan He,Jinyan Liu,Katherine McMahan,Amanda J. Martinot,David R. Martinez,Tori Giffin,David L. Hope,Shivani A. Patel,Daniel Sellers,Owen Sanborn,Julia Barrett,Xiaowen Liu,Andrew C. Cole,Laurent Pessaint,Daniel Valentin,Zack Flinchbaugh,Jake Yalley-Ogunro,Jeanne Muench,Renita Brown,Anthony L. Cook,Elyse Teow,Hanne Leth Andersen,Mark G. Lewis,Adrianus C. M. Boon,Ralph S. Baric,Stefan O. Mueller,Benjamin Petsch,Dan H. Barouch,Dan H. Barouch +34 more
TL;DR: In this paper, a head-to-head study of the immunogenicity and protective efficacy of CVnCoV and CV2CoV in nonhuman primates was conducted.
Journal ArticleDOI
Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques.
Xuan He,Abishek Chandrashekar,Roland Zahn,Frank Wegmann,Jingyou Yu,Noe B. Mercado,Katherine McMahan,Amanda J. Martinot,Cesar Piedra-Mora,Sidney Beecy,Sarah Ducat,Ronnie Chamanza,Sietske K. Rosendahl Huber,Marjolein van Heerden,Leslie van der Fits,Erica N. Borducchi,Michelle A. Lifton,Jinyan Liu,Felix Nampanya,Shivani A. Patel,Lauren Peter,Lisa H. Tostanoski,Laurent Pessaint,Alex Van Ry,Brad Finneyfrock,Jason Velasco,Elyse Teow,Renita Brown,Anthony L. Cook,Hanne Leth Andersen,Mark G. Lewis,Hanneke Schuitemaker,Dan H. Barouch,Dan H. Barouch +33 more
TL;DR: In this article, a single immunization with an Adenovirus serotype 26 vector-based vaccine expressing an optimized SARS-CoV-2 spike (Ad26.COV2.S) protected rhesus macaques against SARS co-v-2 challenge.
Journal ArticleDOI
Protective efficacy of Ad26.COV2.S against SARS-CoV-2 B.1.351 in macaques.
Jingyou Yu,Lisa H. Tostanoski,Noe B. Mercado,Katherine McMahan,Jinyan Liu,Catherine Jacob-Dolan,Catherine Jacob-Dolan,Abishek Chandrashekar,Caroline Atyeo,Caroline Atyeo,David R. Martinez,Tochi Anioke,Esther A. Bondzie,Aiquan Chang,Aiquan Chang,Sarah Gardner,Victoria M. Giffin,David L. Hope,Felix Nampanya,Joseph P. Nkolola,Shivani A. Patel,Owen Sanborn,Daniel Sellers,Huahua Wan,Tammy Hayes,Katherine Bauer,Laurent Pessaint,Daniel Valentin,Zack Flinchbaugh,Renita Brown,Anthony L. Cook,Deandre Bueno-Wilkerson,Elyse Teow,Hanne Leth Andersen,Mark G. Lewis,Amanda J. Martinot,Ralph S. Baric,Galit Alter,Frank Wegmann,Roland Zahn,Hanneke Schuitemaker,Dan H. Barouch,Dan H. Barouch,Dan H. Barouch +43 more
TL;DR: Ad26.COV2.S as discussed by the authors elicits humoral and cellular immune responses that cross-react with the B.1.351 challenge in rhesus macaques.