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Amanda M. Fenner
Researcher at University of Connecticut
Publications - 7
Citations - 657
Amanda M. Fenner is an academic researcher from University of Connecticut. The author has contributed to research in topics: Depsipeptide & Marine invertebrates. The author has an hindex of 5, co-authored 7 publications receiving 553 citations. Previous affiliations of Amanda M. Fenner include University of California, San Diego & University of Montana.
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Journal ArticleDOI
Molecular Networking as a Dereplication Strategy
Jane Y. Yang,Laura M. Sanchez,Christopher M. Rath,Xueting Liu,Paul D. Boudreau,Nicole Bruns,Evgenia Glukhov,Anne Wodtke,Rafael de Felício,Rafael de Felício,Amanda M. Fenner,Weng Ruh Wong,Roger G. Linington,Lixin Zhang,Hosana Maria Debonsi,William H. Gerwick,Pieter C. Dorrestein +16 more
TL;DR: It is demonstrated here that molecular networking, an approach that organizes MS/MS data based on chemical similarity, is a powerful complement to traditional dereplication strategies, and is applied to a diverse array of marine and terrestrial microbial samples.
Journal ArticleDOI
Drug Discovery from Marine Microbes
TL;DR: The marine environment has been a source of more than 20,000 inspirational natural products discovered over the past 50 years, and from these efforts, 9 approved drugs and 12 current clinical trial agents have been discovered, either as natural products or as molecules inspired from the natural product structure.
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Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activity.
Marcy J. Balunas,Roger G. Linington,Kevin Tidgewell,Amanda M. Fenner,Luis-David Ureña,Gina Della Togna,Dennis E. Kyle,William H. Gerwick +7 more
TL;DR: Spectroscopic and stereochemical data for dragonamide E and herbamide B are presented as well as comparisons of biological activity within the dragonamide compound family, and biosynthetic differences among marine compounds with a terminal free amide are discussed.
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Discovery and Synthesis of Caracolamide A, an Ion Channel Modulating Dichlorovinylidene Containing Phenethylamide from a Panamanian Marine Cyanobacterium cf. Symploca Species
C. Benjamin Naman,Jehad Almaliti,Jehad Almaliti,Lorene Armstrong,Lorene Armstrong,Eduardo J. E. Caro-Diaz,Marsha L. Pierce,Evgenia Glukhov,Amanda M. Fenner,Carmenza Spadafora,Hosana Maria Debonsi,Pieter C. Dorrestein,Thomas F. Murray,William H. Gerwick +13 more
TL;DR: A recent untargeted metabolomics investigation into the chemical profile of 10 organic extracts from cf.
Journal ArticleDOI
Medusamide A, a Panamanian Cyanobacterial Depsipeptide with Multiple β-Amino Acids.
Amanda M. Fenner,Niclas Engene,Carmenza Spadafora,William H. Gerwick,William H. Gerwick,Marcy J. Balunas,Marcy J. Balunas +6 more
TL;DR: This is the first report of multiple Amha residues and contiguous β-amino acid residues within a single cyclic peptide-type natural product.