Amélie Dendooven

TL;DR: An overview of the factors contributing to the pathophysiology of UUO is presented, highlighting the role of oxidative stress.

TL;DR: The morphology of the glomerulus will be discussed, with a focus on the podocyte, its interactions with surrounding cells, and the highly differentiated slit diaphragm separating the apical from the basal membrane.

TL;DR: It is demonstrated that neonatal colonization of gut microbiota influences generalized autoimmunity in adult life, and antinuclear antibody production is influenced by the presence of commensal gut flora, in particular increased colonization with segmented filamentous bacteria, and IL‐17 receptor signaling.

TL;DR: Connective tissue growth factor is associated with disease severity parameters and outcome in fibrotic disease and may have diagnostic and prognostic values, however, CTGF ELISA needs standardization.

TL;DR: Although increases in plasma ddcfDNA% are associated with graft injury, plasma ddCFDNA does not outperform the diagnostic capacity of the serum creatinine in the diagnosis of acute rejection.