Amy Li

TL;DR: In this paper, the authors investigated Treg cell function in a genetically engineered mouse model of lung adenocarcinoma and found that Treg cells suppressed anti-tumor responses in tumor-associated tertiary lymphoid structures (TA-TLSs).

TL;DR: It is identified parasite variants that associate with relapsing disease, including amino acid substitutions in the atovaquone-binding regions of cytochrome b (cytb) and the azithromycin-binding region of ribosomal protein subunit L4 (rpl4).

TL;DR: In this paper, the interplay between responses and its impact on T-cell function and tumor control was studied in mouse lung adenocarcinoma, where the authors found that immunodominance is established in tumors, wherein CD8 T-cells expansion is predominantly driven by the antigen that most stably binds MHC.

TL;DR: In this paper, the authors correlated quantities of circulating T and B cell subsets at baseline with longitudinal serologic responses to SARS-CoV-2 mRNA vaccination in heart and lung transplant recipients.

TL;DR: In a pair of papers in Immunity and Cell, Ghosh and colleagues show that the canonical NF-κB subunits p65 and c-Rel have non-redundant, critical roles in promoting Treg cell development and function.