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Andreas G. Ladurner

Researcher at Ludwig Maximilian University of Munich

Publications -  97
Citations -  8634

Andreas G. Ladurner is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Chromatin & Histone. The author has an hindex of 43, co-authored 94 publications receiving 7723 citations. Previous affiliations of Andreas G. Ladurner include Center for Integrated Protein Science Munich & European Bioinformatics Institute.

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A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain.

Susanne Till, +8 more
- 23 Sep 2007 - 
TL;DR: A repetitive motif within Tas3, termed the 'Argonaute hook', is described that is conserved from yeast to humans and binds Ago proteins through their PIWI domains in vitro and in vivo and may be important regulatory components of effector complexes in RNA interference.
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Bromodomains mediate an acetyl-histone encoded antisilencing function at heterochromatin boundaries.

Andreas G. Ladurner, +3 more
- 01 Feb 2003 - 
TL;DR: It is shown that yeast Bdf1 bromodomains recognize endogenous acetyl-histone H3/H4 as a mechanism for chromatin association in vivo and suggest an active role for BDF1 in euchromatin maintenance and antisilencing through a histone tail-encoded boundary function.
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The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks

Ammar A E Ali, +12 more
- 01 Jul 2012 - 
TL;DR: The crystal structure of the human PARP1-DBD bound to a DNA break is determined and reveals a dimeric assembly whereby ZnF1 andZnF2 domains from separatePARP1 molecules form a strand-break recognition module that helps activate PARP 1 by facilitating its dimerization and consequent trans-automodification.
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Structures of Drosophila Cryptochrome and Mouse Cryptochrome1 Provide Insight into Circadian Function

Anna Czarna, +7 more
- 06 Jun 2013 - 
TL;DR: The structure of a mammalian cryptochrome1 protein may catalyze the development of CRY chemical probes and the design of therapeutic metabolic modulators.
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Histone macroH2A isoforms predict the risk of lung cancer recurrence

Judith C. Sporn, +7 more
- 24 Sep 2009 - 
TL;DR: It is shown that expression of histone macroH2A1.1 and macroH1A2 predicts lung cancer recurrence, identifying these histone variants as a novel tool for an improved risk stratification of cancer patients.