A
Andrew J. Fox
Researcher at Manchester Royal Infirmary
Publications - 97
Citations - 7911
Andrew J. Fox is an academic researcher from Manchester Royal Infirmary. The author has contributed to research in topics: Campylobacter jejuni & Multilocus sequence typing. The author has an hindex of 44, co-authored 96 publications receiving 7655 citations. Previous affiliations of Andrew J. Fox include Health Protection Agency & University College London.
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Journal ArticleDOI
Multilocus Sequence Typing System for Campylobacter jejuni
Kate E. Dingle,Frances M. Colles,David R. A. Wareing,Roisin Ure,Andrew J. Fox,F. E. Bolton,H. J. Bootsma,Rob J. L. Willems,Rachel Urwin,Martin C. J. Maiden +9 more
TL;DR: A multilocus sequence typing (MLST) system for this organism is described, which exploits the genetic variation present in seven housekeeping loci to determine the genetic relationships among isolates and indicates that C. jejuni is genetically diverse, with a weakly clonal population structure.
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Simultaneous Detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in Suspected Cases of Meningitis and Septicemia Using Real-Time PCR
Caroline Corless,Malcolm Guiver,Ray Borrow,Valerie Edwards-Jones,Andrew J. Fox,Edward B. Kaczmarski +5 more
TL;DR: A single-tube 5′ nuclease multiplex PCR assay was developed on the ABI 7700 Sequence Detection System (TaqMan) for the detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae from clinical samples of cerebrospinal fluid, plasma, serum, and whole blood.
Journal ArticleDOI
Contamination and Sensitivity Issues with a Real-Time Universal 16S rRNA PCR
Caroline E. Corless,Malcolm Guiver,Ray Borrow,Valerie Edwards-Jones,Edward B. Kaczmarski,Andrew J. Fox +5 more
TL;DR: A set of universal oligonucleotide primers specific for the conserved regions of the eubacterial 16S rRNA gene was designed for use with the real-time PCR Applied Biosystems 7700 (TaqMan) system, but problems were noted with the use of this gene as an amplification target.
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Rapid detection of the O25b-ST131 clone of Escherichia coli encompassing the CTX-M-15-producing strains
Olivier Clermont,Hiran Dhanji,Mathew Upton,Tarek M. Gibreel,Andrew J. Fox,David A. Boyd,Michael R. Mulvey,Patrice Nordmann,Etienne Ruppé,J. L. Sarthou,Thierry Frank,Thierry Frank,Sophie Vimont,Guillaume Arlet,Catherine Branger,Neil Woodford,Erick Denamur +16 more
TL;DR: A PCR-based assay is developed that easily identifies a clone with high likelihood of producing ESBLs, including CTX-M-15, which represents 3% of non-ESBL B2 isolates originating from urinary tract infections in Paris.
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Serogroup W135 meningococcal disease in Hajj pilgrims.
Muhamed-Kheir Taha,Mark Achtman,Jean-Michel Alonso,Brian Greenwood,Mary Ramsay,Andrew J. Fox,Steve J. Gray,Edward B. Kaczmarski +7 more
TL;DR: Characterisation of isolates showed them to be of clonal origin (ET-37) and closely related to other meningococci with an established propensity to cause disease clusters and a reappraisal of vaccination strategies for travellers is required.