O
Olivier Clermont
Researcher at University of Paris
Publications - 153
Citations - 18809
Olivier Clermont is an academic researcher from University of Paris. The author has contributed to research in topics: Escherichia coli & Virulence. The author has an hindex of 50, co-authored 141 publications receiving 16562 citations. Previous affiliations of Olivier Clermont include Paris-Sorbonne University & Paris Diderot University.
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Journal ArticleDOI
Identification and characterization of a spinal muscular atrophy-determining gene
Suzie Lefebvre,Lydie Burglen,Sophie Reboullet,Olivier Clermont,Philippe Burlet,Louis Viollet,Bernard Bénichou,Corinne Cruaud,Philippe Millasseau,Massimo Zeviani,Denis Le Paslier,Jean Frézal,Daniel Cohen,Jean Weissenbach,Arnold Munnich,Judith Melki +15 more
TL;DR: The inverted duplication of a 500 kb element in normal chromosomes is described and the critical region is narrowed to 140 kb within the telomeric region, suggesting that this gene, termed the survival motor neuron (SMN) gene, is an SMA-determining gene.
Journal ArticleDOI
Rapid and simple determination of the Escherichia coli phylogenetic group.
TL;DR: In this paper, a simple and rapid phylogenetic grouping technique based on triplex PCR was proposed, which uses a combination of two genes (chuA and yjaA) and an anonymous DNA fragment, was tested with 230 strains and showed excellent correlation with reference methods.
Journal ArticleDOI
The Clermont Escherichia coli phylo‐typing method revisited: improvement of specificity and detection of new phylo‐groups
Olivier Clermont,Olivier Clermont,Julia K. Christenson,Erick Denamur,Erick Denamur,David M. Gordon +5 more
TL;DR: A new PCR-based method is developed that enables an E. coli isolate to be assigned to one of the eight phylo-groups and which allows isolates that are members of the other cryptic clades (II to V) of Escherichia to be identified.
Journal ArticleDOI
Organised Genome Dynamics in the Escherichia coli Species Results in Highly Diverse Adaptive Paths
Marie Touchon,Marie Touchon,Claire Hoede,Olivier Tenaillon,Valérie Barbe,Simon Baeriswyl,Philippe Bidet,Edouard Bingen,Stéphane Bonacorsi,Christiane Bouchier,Odile Bouvet,Alexandra Calteau,Hélène Chiapello,Olivier Clermont,Stéphane Cruveiller,Antoine Danchin,Médéric Diard,Carole Dossat,Meriem El Karoui,Eric Frapy,Louis Garry,Jean Marc Ghigo,Anne-Marie Gilles,James R. Johnson,James R. Johnson,Chantal Le Bouguénec,Mathilde Lescat,Sophie Mangenot,Vanessa Martinez-Jéhanne,Ivan Matic,Xavier Nassif,Sophie Oztas,Marie-Agnès Petit,Christophe Pichon,Zoé Rouy,Claude Saint Ruf,Dominique Schneider,Jérôme Tourret,Benoit Vacherie,David Vallenet,Claudine Médigue,Eduardo P. C. Rocha,Eduardo P. C. Rocha,Erick Denamur +43 more
TL;DR: An important adaptive role for metabolism diversification within group B2 and Shigella strains is found, but few or no extraint intestinal virulence-specific genes are identified, which could render difficult the development of a vaccine against extraintestinal infections.
Journal ArticleDOI
Correlation between severity and SMN protein level in spinal muscular atrophy.
Suzie Lefebvre,Philippe Burlet,Qing Liu,Solange Bertrandy,Olivier Clermont,Arnold Munnich,Gideon Dreyfuss,Judith Melki +7 more
TL;DR: A marked deficiency of the SMN protein in SMA is shown and the molecular mechanism underlying the pathogenesis of the disease is elucidated by western blot and immunohistochemical analyses using antibodies raised against theSMN protein.