A
Andrew Pink
Researcher at Guy's and St Thomas' NHS Foundation Trust
Publications - 84
Citations - 2321
Andrew Pink is an academic researcher from Guy's and St Thomas' NHS Foundation Trust. The author has contributed to research in topics: Medicine & Atopic dermatitis. The author has an hindex of 17, co-authored 54 publications receiving 1559 citations. Previous affiliations of Andrew Pink include University of Nottingham & St. John's University.
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Journal ArticleDOI
Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis
Alexandros Onoufriadis,Michael A. Simpson,Andrew Pink,Paola Di Meglio,Catherine H. Smith,Venu Pullabhatla,Jo Knight,Sarah L. Spain,Frank O. Nestle,A. David Burden,Francesca Capon,Richard C. Trembath,Jonathan Barker +12 more
TL;DR: Findings suggest loss of function of IL36RN as the genetic basis of GPP and implicate innate immune dysregulation in this severe episodic inflammatory disease, thereby highlighting IL-1 signaling as a potential target for therapeutic intervention.
Journal ArticleDOI
Abrocitinib versus Placebo or Dupilumab for Atopic Dermatitis.
Thomas Bieber,Eric L. Simpson,Jonathan I. Silverberg,Diamant Thaçi,Carle Paul,Andrew Pink,Yoko Kataoka,Chia-Yu Chu,Marco DiBonaventura,Ricardo Rojo,Jeremias Antinew,Ileana A. Ionita,Rodney Sinclair,Seth Forman,Jacek Zdybski,Pinaki Biswas,Bimal Malhotra,Fan Zhang,Hernan Valdez +18 more
TL;DR: In this article, the oral Janus kinase 1 (JAK1) inhibitor abrocitinib, which reduces interleukin-4 and interleucin-13 signaling, was investigated for the treatment of atopic dermatitis.
Journal ArticleDOI
Rare pathogenic variants in IL36RN underlie a spectrum of psoriasis-associated pustular phenotypes.
Niovi Setta-Kaffetzi,Alexander A. Navarini,Varsha M. Patel,Venu Pullabhatla,Andrew Pink,Siew Eng Choon,M Allen,A. David Burden,Christopher E.M. Griffiths,Marieke M B Seyger,Brian Kirby,Richard C. Trembath,Richard C. Trembath,Michael A. Simpson,Catherine H. Smith,Francesca Capon,Jonathan Barker +16 more
Journal ArticleDOI
γ-Secretase mutations in hidradenitis suppurativa: new insights into disease pathogenesis.
Andrew Pink,Michael A. Simpson,N. Desai,Richard C. Trembath,Richard C. Trembath,Jonathan Barker +5 more
TL;DR: The recent genetic data is reviewed, how they inform disease pathogenesis, and the long-term implications in HS and related diseases are reviewed.
Journal ArticleDOI
Tralokinumab plus topical corticosteroids for the treatment of moderate-to-severe atopic dermatitis: results from the double-blind, randomized, multicentre, placebo-controlled phase III ECZTRA 3 trial.
Jonathan I. Silverberg,Darryl Toth,T. Bieber,Andrew F Alexis,Boni E. Elewski,Andrew Pink,DirkJan Hijnen,T.N. Jensen,Bo Bang,Christina Olsen,Azra Kurbasic,Stephan Weidinger +11 more
TL;DR: Tralokinumab is a fully human monoclonal antibody that specifically neutralizes interleukin‐13, a key driver of atopic dermatitis (AD).