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Angela Woods
Researcher at Hammersmith Hospital
Publications - 22
Citations - 7282
Angela Woods is an academic researcher from Hammersmith Hospital. The author has contributed to research in topics: AMPK & Protein kinase A. The author has an hindex of 18, co-authored 21 publications receiving 6920 citations. Previous affiliations of Angela Woods include Medical Research Council & Université catholique de Louvain.
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Journal ArticleDOI
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade
Angela Woods,Stephen R. Johnstone,Kristina Dickerson,Fiona C. Leiper,Lee G.D. Fryer,Dietbert Neumann,Uwe Schlattner,Theo Wallimann,Marian Carlson,David Carling +9 more
TL;DR: The results identify a link between two protein kinases, previously thought to lie in unrelated, distinct pathways, that are associated with human diseases.
Journal ArticleDOI
Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells
Angela Woods,Kristina Dickerson,Richard Heath,Seung-Pyo Hong,Milica Momcilovic,Stephen R. Johnstone,Marian Carlson,David Carling +7 more
TL;DR: It is shown that AMPK is also activated by Ca(2+)/calmodulin-dependent protein kinase kinase (CaMKK) and suggested that AM PK may play a role in Ca( 2+)-mediated signal transduction pathways.
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Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase
Simon A. Hawley,Matthew Davison,Angela Woods,Stephen P. Davies,Raj K. Beri,David Carling,D. Grahame Hardie +6 more
TL;DR: This finding is consistent with the recent report that the AMP-activated protein kinase kinase can slowly phosphorylate and activate calmodulin-dependentprotein kinase I, at least in vitro.
Journal ArticleDOI
AMP-activated Protein Kinase Plays a Role in the Control of Food Intake
Ulrika Andersson,Karin Filipsson,Caroline R. Abbott,Angela Woods,Kirsty L. Smith,Stephen R. Bloom,David Carling,Caroline J. Small +7 more
TL;DR: It is demonstrated that counter-regulatory hormones involved in appetite control regulate AMPK activity and that pharmacological activation of AMPK in the hypothalamus increases food intake, and that AMPK is identified as a novel target for anti-obesity drugs.
Journal ArticleDOI
Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo
TL;DR: SNF1 undergoes a time-dependent increase in activity during growth in glucose-derepressing conditions, providing the first evidence that SNF1 activity is regulated by the level of available glucose.