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Anil G. Menon

Researcher at University of Cincinnati Academic Health Center

Publications -  95
Citations -  8161

Anil G. Menon is an academic researcher from University of Cincinnati Academic Health Center. The author has contributed to research in topics: Gene & Chromosomal translocation. The author has an hindex of 43, co-authored 95 publications receiving 7820 citations. Previous affiliations of Anil G. Menon include Harvard University & University of Bonn.

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Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis.

TL;DR: The formation of malignant neurofibrosarcomas may result from several independent genetic events including mutation of the NF1 gene, whose mechanism of tumorigenesis remains uncertain, and subsequent loss of a "tumor suppressor" gene on 17p, most likely p53.
Journal Article

Mutations of the PATCHED Gene in Several Types of Sporadic Extracutaneous Tumors

TL;DR: It is found that 2 of 14 sporadic medulloblastomas bear somatic nonsense mutations in one copy of the gene and also deletion of the other copy, and that missense mutations in PTCH are identified in two of seven breast carcinomas, one of nine meningiomas, and one colon cancer cell line.
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Salivary acinar cells from aquaporin 5-deficient mice have decreased membrane water permeability and altered cell volume regulation.

TL;DR: In this paper, the authors show that the decreased salivary flow rate and increased tonicity of the saliva secreted by Aqp5 −/− mice in response to pilocarpine stimulation are not caused by changes in whole body fluid homeostasis, indicated by similar blood gas and electrolyte concentrations in urine and blood in wild-type and AQP5− mice.