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Anja Telzerow
Researcher at European Bioinformatics Institute
Publications - 11
Citations - 1693
Anja Telzerow is an academic researcher from European Bioinformatics Institute. The author has contributed to research in topics: Microbiome & Biology. The author has an hindex of 5, co-authored 7 publications receiving 1153 citations. Previous affiliations of Anja Telzerow include Max Planck Society & Heidelberg University.
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Journal ArticleDOI
Extensive impact of non-antibiotic drugs on human gut bacteria
Lisa A. Maier,Mihaela Pruteanu,Michael Kuhn,Georg Zeller,Anja Telzerow,Exene Erin Anderson,Ana Rita Brochado,Keith C. Fernandez,Hitomi Dose,Hirotada Mori,Kiran Raosaheb Patil,Peer Bork,Athanasios Typas +12 more
TL;DR: For example, this paper screened more than 1,000 marketed drugs against 40 representative gut bacterial strains, and found that 24% of the drugs with human targets, including members of all therapeutic classes, inhibited the growth of at least one strain in vitro.
Journal ArticleDOI
Species-specific activity of antibacterial drug combinations
Ana Rita Brochado,Anja Telzerow,Jacob Bobonis,Manuel Banzhaf,André Mateus,Joel Selkrig,Emily Huth,Stefan Bassler,Jordi Zamarreño Beas,Matylda Zietek,Natalie Ng,Sunniva Foerster,Benjamin Ezraty,Béatrice Py,Frédéric Barras,Frédéric Barras,Mikhail M. Savitski,Peer Bork,Stephan Göttig,Athanasios Typas +19 more
TL;DR: Screening pairwise combinations of antibiotics and other drugs against three bacterial pathogens reveals that antagonistic and synergistic drug–drug interactions are specific to microbial species and strains.
Journal ArticleDOI
A clonal analysis of neural progenitors during axolotl spinal cord regeneration reveals evidence for both spatially restricted and multipotent progenitors
TL;DR: Results suggest that neural progenitor identity is destabilized or altered in the terminal vesicle region, from which clear migration of cells into the surrounding blastema is also observed.
Journal ArticleDOI
Integrin Cytoplasmic Domain-Associated Protein-1 Attenuates Sprouting Angiogenesis
René Brütsch,Sven S. Liebler,Sven S. Liebler,Joycelyn Wüstehube,Joycelyn Wüstehube,Arne Bartol,Arne Bartol,Stefanie E. Herberich,Stefanie E. Herberich,M. Gordian Adam,M. Gordian Adam,Anja Telzerow,Hellmut G. Augustin,Andreas Fischer,Andreas Fischer +14 more
TL;DR: This study identified ICAP1 as a novel regulator to prevent excessive sprouting angiogenesis and global gene expression analyses revealed that theICAP1 effects are mediated by strong activation of DELTA-NOTCH signaling.
Journal ArticleDOI
A faecal microbiota signature with high specificity for pancreatic cancer
Ece Kartal,Thomas Schmidt,Esther Molina-Montes,Sandra Rodriguez-Perales,Jakob Wirbel,Oleksandr M. Maistrenko,Wasiu Akanni,Bilal Alashkar Alhamwe,Renato J. Alves,Alfredo Carrato,Hans-Peter Erasmus,Lidia Estudillo,Fabian Finkelmeier,Anthony Fullam,Anna Głazek,Paulina Gomez-Rubio,Rajna Hercog,Ferris Jung,Stefanie Kandels,Stephan Kersting,Melanie Langheinrich,Mirari Marquez,Xavier Molero,Askarbek N Orakov,Thea Van Rossum,Raúl Torres-Ruiz,Anja Telzerow,Konrad Zych,Vladimir Benes,Georg Zeller,Jonel Trebicka,Francisco X. Real,Núria Malats,Peer Bork +33 more
TL;DR: Faecal metagenomic classifiers performed much better than saliva-based classifiers and identified patients with PDAC with an accuracy of up to 0.84 area under the receiver operating characteristic curve (AUROC) based on a set of 27 microbial species, with consistent accuracy across early and late disease stages.