M
Melanie Langheinrich
Publications - 13
Citations - 691
Melanie Langheinrich is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 1, co-authored 1 publications receiving 322 citations.
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Journal ArticleDOI
Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study
Maxime J M van der Valk,Maxime J M van der Valk,Denise E. Hilling,Denise E. Hilling,Esther Bastiaannet,Elma Meershoek-Klein Kranenbarg,Geerard L. Beets,Geerard L. Beets,Nuno Figueiredo,Angelita Habr-Gama,Rodrigo Oliva Perez,Andrew G Renehan,Andrew G Renehan,Cornelis J.H. van de Velde,Madeleine Ahlberg,Ane L Appelt,Oktar Asoglu,Maria-Theresa Bär,Rita Barroca,Regina G. H. Beets-Tan,Eric Belgers,Robbert J I Bosker,Stephanie O. Breukink,Krysztof Bujko,Carlos Carvalho,Christopher M. Cunningham,Ben Creavin,André D’Hoore,Jean-Pierre Gerard,Simon Gollins,Christiaan Hoff,Fabian A. Holman,Britt J. P. Hupkens,Soledad Iseas,Anders Jakobsen,Amir Keshvari,Sietze A Koopal,Miranda Kusters,Melanie Langheinrich,Jeroen W. A. Leijtens,Monique Maas,Lee Malcomson,Zamam Z Mamedli,Anna Martling,Klaus E. Matzel,Jarno Melenhorst,María L Morici,Sthela M. Murad-Regadas,Sarah T O'Dwyer,Koen C.M.J. Peeters,Isadora Rosa,Gustavo Rossi,Harm J. T. Rutten,Fernando Sanchez Loria,Marit E van der Sande,Guilherme Pagin São Julião,Mark P Saunders,Arthur Sun Myint,Hedwig van der Sluis,Renaud Schiappa,Nigel Scott,Jan H.M.B. Stoot,A Koen Talsma,Isabelle Terrasson,Handan Tokmak,Carlos A. Vaccaro,Alexander L Vahrmeijer,Daria K Wasowicz,Henderik L Westreenen,Des C. Winter,Albert Wolthuis,David D. E. Zimmerman +71 more
TL;DR: This dataset has the largest series of patients with rectal cancer treated with a W&W approach, consisting of approximately 50% data from previous cohort series and 50% unpublished data.
Journal ArticleDOI
A faecal microbiota signature with high specificity for pancreatic cancer
Ece Kartal,Thomas Schmidt,Esther Molina-Montes,Sandra Rodriguez-Perales,Jakob Wirbel,Oleksandr M. Maistrenko,Wasiu Akanni,Bilal Alashkar Alhamwe,Renato J. Alves,Alfredo Carrato,Hans-Peter Erasmus,Lidia Estudillo,Fabian Finkelmeier,Anthony Fullam,Anna Głazek,Paulina Gomez-Rubio,Rajna Hercog,Ferris Jung,Stefanie Kandels,Stephan Kersting,Melanie Langheinrich,Mirari Marquez,Xavier Molero,Askarbek N Orakov,Thea Van Rossum,Raúl Torres-Ruiz,Anja Telzerow,Konrad Zych,Vladimir Benes,Georg Zeller,Jonel Trebicka,Francisco X. Real,Núria Malats,Peer Bork +33 more
TL;DR: Faecal metagenomic classifiers performed much better than saliva-based classifiers and identified patients with PDAC with an accuracy of up to 0.84 area under the receiver operating characteristic curve (AUROC) based on a set of 27 microbial species, with consistent accuracy across early and late disease stages.
Journal ArticleDOI
Metagenomic identification of microbial signatures predicting pancreatic cancer from a multinational study.
Naoyoshi Nagata,Suguru Nishijima,Yasushi Kojima,Yuya Hisada,Koh Imbe,Tohru Miyoshi-Akiyama,Wataru Suda,Moto Kimura,Ryo Aoki,Katsunori Sekine,Mitsuru Ohsugi,K. Miki,Tsuyoshi Osawa,Kohjiro Ueki,Shinichi Oka,Masashi Mizokami,Ece Kartal,Thomas Schmidt,Esther Molina-Montes,Lidia Estudillo,Núria Malats,Jonel Trebicka,Stephan Kersting,Melanie Langheinrich,Peer Bork,Naomi Uemura,Takao Itoi,Takashi Kawai +27 more
TL;DR: The identification of shared gut microbial signatures for PDAC in Asian and European cohorts indicates the presence of robust and global gut microbial biomarkers.
Journal ArticleDOI
The use of single-stapling techniques reduces anastomotic complications in minimal-invasive rectal surgery
Maximilian Brunner,Alaa Zu’bi,Klaus Weber,Axel Denz,Melanie Langheinrich,Stephan Kersting,Georg F. Weber,Robert Grützmann,Christian Krautz +8 more
TL;DR: In this article , the authors investigated whether using single-stapling techniques (SST) instead of the double-stapling technique (DST) is associated with a lower rate of anastomotic complications.
Journal ArticleDOI
Orchestrating Treatment Modalities in Metastatic Pancreatic Neuroendocrine Tumors—Need for a Conductor
Alexander Siebenhüner,Melanie Langheinrich,Juliane Friemel,Niklaus Schäfer,Dilmurodjon Eshmuminov,Kuno Lehmann +5 more
TL;DR: The focus of this review is to highlight the right time-point for surgery in the setting of the multimodal treatment of an advanced pancreatic neuroendocrine tumor.