Ann E. Mayne

TL;DR: Combining short-term antiretroviral therapy with specific anti-integrin treatment sustains low viral loads in monkeys and allows macaques to effectively control viremia and reconstitute their immune systems without a need for further therapy.

TL;DR: Findings for the first time suggest that such abnormalities may in concert lead to the initiation and perpetuation of an autoimmune process, which leads to cardiac failure and disease.

TL;DR: Comparison of the relative bioactivity of the immunoaffinity-purified recombinant rhesus macaque IL-4, IL-15, and IFN-gamma with commercially available human recombinant cytokines is described herein and a phylogenetic analysis of the published sequences of select cytokines from other species, along with those of the nonhuman primates are described.

TL;DR: It is shown that the administration of an anti-α4β7 monoclonal antibody just prior to and during acute infection protects rhesus macaques from transmission following repeated low-dose intravaginal challenges with SIVmac251.

TL;DR: Using tetanus toxoid (TT) and influenza (Flu) immunization of rhesus macaques as a model, the effect of IL-2 and IL-15 on the generation and maintenance of antigen specific memory T cells was evaluated following primary and secondary immunization.