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Anna-Karin L. Robertson
Researcher at Yale University
Publications - 21
Citations - 5799
Anna-Karin L. Robertson is an academic researcher from Yale University. The author has contributed to research in topics: Inflammation & Immune system. The author has an hindex of 17, co-authored 21 publications receiving 5285 citations. Previous affiliations of Anna-Karin L. Robertson include Karolinska University Hospital & Howard Hughes Medical Institute.
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Journal ArticleDOI
Transforming growth factor-beta regulation of immune responses.
TL;DR: This review highlights the findings that have advanced the understanding of TGF-beta in the immune system and in disease.
Journal ArticleDOI
Natural regulatory T cells control the development of atherosclerosis in mice.
Hafid Ait-Oufella,Benoît L. Salomon,Stephane Potteaux,Anna-Karin L. Robertson,Pierre Gourdy,Joffrey Zoll,Régine Merval,Bruno Esposito,José L. Cohen,Sylvain Fisson,Richard A. Flavell,Göran K. Hansson,David Klatzmann,Alain Tedgui,Ziad Mallat +14 more
TL;DR: It is shown that naturally arising CD4+CD25+ regulatory T cells, which actively maintain immunological tolerance to self and nonself antigens, are powerful inhibitors of atherosclerosis in several mouse models.
Journal ArticleDOI
Inflammation and atherosclerosis
TL;DR: In this paper, the authors describe the inflammatory process of atherosclerosis, which occurs when cholesterol-containing low-density lipoproteins accumulate in the intima and activate the endothelium.
Journal ArticleDOI
Disruption of TGF-β signaling in T cells accelerates atherosclerosis
Anna-Karin L. Robertson,Mats Rudling,Xinghua Zhou,Leonid Gorelik,Richard A. Flavell,Göran K. Hansson +5 more
TL;DR: Results show that abrogation of T GF-β signaling in T cells increases atherosclerosis and suggest that TGF-β reduces Atherosclerosis by dampening T cell activation, and inhibition of T cellactivation may represent a strategy for antiatherosclerotic therapy.
Journal ArticleDOI
T Cells in Atherogenesis. For Better or For Worse
TL;DR: This review summarizes knowledge of T cells in atherogenesis, their potential antigens, their contact-dependent activities, and their secretion of inflammatory and antiinflammatory mediators, aiming to illustrate how T cells can aggravate or attenuate this disease through cross-talk with other cells within or outside the atherosclerotic plaque.