Anne Chevallereau

TL;DR: It is demonstrated that bacteria with CRISPR-Cas resistance are still partially immune to Acr-encoding phage, which helps elucidate how interactions between phage-encoded immune suppressors and the CRISpr systems they target shape bacteria-phage population dynamics.

TL;DR: A review of the current knowledge of the composition and evolution of phage communities, as well as their roles in controlling the population and evolutionary dynamics of bacterial communities is provided in this article.

TL;DR: It is found that RNA-based regulation plays a central role in PAK_P3 lifecycle as antisense transcripts are produced mainly during the early stage of infection and viral small non coding RNAs are massively expressed at the end of infection.

TL;DR: It is shown that type I CRISPR–Cas immune systems cannot eliminate temperate bacteriophages from bacterial populations and—in this context—the systems impose immunopathological costs on the host, creating selective pressures that may explain their patchy distribution in bacteria.

TL;DR: Bacteriophage treatment was not associated with overinflammation but in contrast tended to lower inflammation and provided a faster correction of blood cell count abnormalities than did antibiotics, and the rapid lysis of bacteria by bacteriophages in vivo does not increase the innate inflammatory response compared to that with antibiotic treatment.