S
Stineke van Houte
Researcher at University of Exeter
Publications - 51
Citations - 1904
Stineke van Houte is an academic researcher from University of Exeter. The author has contributed to research in topics: CRISPR & Population. The author has an hindex of 19, co-authored 42 publications receiving 1351 citations. Previous affiliations of Stineke van Houte include Wageningen University and Research Centre & University of Bologna.
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Journal ArticleDOI
Parasite Exposure Drives Selective Evolution of Constitutive versus Inducible Defense
Edze R. Westra,Stineke van Houte,Sam Oyesiku-Blakemore,Ben Makin,Jenny M. Broniewski,Alex Best,Joseph Bondy-Denomy,Alan R. Davidson,Mike Boots,Angus Buckling +9 more
TL;DR: The general theoretical model and experimental evolution are teased apart the mechanism that drives their evolution and show that infection risk determines the relative investment in the two arms of defense.
Journal ArticleDOI
The diversity-generating benefits of a prokaryotic adaptive immune system
Stineke van Houte,Alice K. E. Ekroth,Jenny M. Broniewski,Hélène Chabas,Hélène Chabas,Ben Ashby,Ben Ashby,Joseph Bondy-Denomy,Sylvain Gandon,Mike Boots,Mike Boots,Steve Paterson,Angus Buckling,Edze R. Westra +13 more
TL;DR: It is proposed that the resulting short-lived nature of CRISPR-dependent bacteria–virus coevolution has provided strong selection for the evolution of sophisticated virus-encoded anti-CRISPR mechanisms.
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Evolutionary Ecology of Prokaryotic Immune Mechanisms
TL;DR: The short- and long-term costs and benefits of the different resistance strategies and, hence, the ecological conditions that are likely to favor the different strategies alone and in combination are discussed.
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Anti-CRISPR Phages Cooperate to Overcome CRISPR-Cas Immunity
Mariann Landsberger,Sylvain Gandon,Sean Meaden,Clare Rollie,Anne Chevallereau,Hélène Chabas,Angus Buckling,Edze R. Westra,Stineke van Houte +8 more
TL;DR: It is demonstrated that bacteria with CRISPR-Cas resistance are still partially immune to Acr-encoding phage, which helps elucidate how interactions between phage-encoded immune suppressors and the CRISpr systems they target shape bacteria-phage population dynamics.
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Interactions between bacterial and phage communities in natural environments.
TL;DR: A review of the current knowledge of the composition and evolution of phage communities, as well as their roles in controlling the population and evolutionary dynamics of bacterial communities is provided in this article.