A
Anne Sofie Andreasen
Researcher at University of Copenhagen
Publications - 29
Citations - 3518
Anne Sofie Andreasen is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Medicine & Intensive care unit. The author has an hindex of 10, co-authored 20 publications receiving 2758 citations. Previous affiliations of Anne Sofie Andreasen include Copenhagen University Hospital & Herlev Hospital.
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Journal ArticleDOI
Gut Microbiota in Human Adults with Type 2 Diabetes Differs from Non-Diabetic Adults
Nadja Larsen,Finn K. Vogensen,Frans van den Berg,Dennis Sandris Nielsen,Anne Sofie Andreasen,Bente Klarlund Pedersen,Waleed Abu Al-Soud,Søren J. Sørensen,Lars Hestbjerg Hansen,Mogens Jakobsen +9 more
TL;DR: The results of this study indicate that type 2 diabetes in humans is associated with compositional changes in intestinal microbiota and the level of glucose tolerance should be considered when linking microbiota with metabolic diseases such as obesity and developing strategies to control metabolic diseases by modifying the gut microbiota.
Journal ArticleDOI
Effects of Lactobacillus acidophilus NCFM on insulin sensitivity and the systemic inflammatory response in human subjects
Anne Sofie Andreasen,Nadja Larsen,Theis Pedersen-Skovsgaard,Ronan M. G. Berg,Kirsten Møller,Kira Dynnes Svendsen,Mogens Jakobsen,Bente Klarlund Pedersen +7 more
TL;DR: Insulin sensitivity was preserved among volunteers in the L. acidophilus NCFM group, whereas it decreased in the placebo group, and the systemic inflammatory response were, however, unaffected by the intervention.
Journal ArticleDOI
Human Endotoxemia as a Model of Systemic Inflammation
Anne Sofie Andreasen,K. S. Krabbe,Rikke Krogh-Madsen,Sarah Taudorf,Bente Klarlund Pedersen,Kirsten Møller +5 more
TL;DR: The activation of inflammatory cascades as well as organ-specific haemodynamic and functional changes after lipopolysaccharide are described, and the limitations of human-experimental models for the study of clinical disease are discussed.
Journal ArticleDOI
Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure
Olav L. Schjørring,Thomas Lass Klitgaard,Anders Perner,Jørn Wetterslev,Theis Lange,Martin Siegemund,Minna Bäcklund,Frederik Keus,Jon Henrik Laake,Matt Morgan,Katrin Thormar,Søren A. Rosborg,Jannie Bisgaard,Annette E.S. Erntgaard,Anne Sofie H. Lynnerup,Rasmus L. Pedersen,Elena Crescioli,Theis C. Gielstrup,Meike T. Behzadi,Lone Musaeus Poulsen,Stine Estrup,Jens Laigaard,Cheme Andersen,Camilla Bekker Mortensen,Björn A. Brand,Jonathan White,Inge Lise Jarnvig,Morten Hylander Møller,Lars Quist,Morten H. Bestle,Martin Schønemann-Lund,Maj K. Kamper,Mathias Hindborg,Alexa Hollinger,Caroline E. Gebhard,Núria Zellweger,Christian S. Meyhoff,Mathias Hjort,Laura K. Bech,Thorbjørn Grøfte,Helle Bundgaard,Lars Ostergaard,Maria A. Thyø,Thomas Hildebrandt,Bülent Uslu,Christoffer Sølling,Nette Møller-Nielsen,Anne Craveiro Brøchner,Morten Borup,Marjatta Okkonen,Willem Dieperink,Ulf Gøttrup Pedersen,Anne Sofie Andreasen,Lone Buus,Tayyba N. Aslam,Robert Winding,Joerg C. Schefold,Stine B. Thorup,Susanne Iversen,Janus Engstrøm,Maj Brit Nørregaard Kjær,Bodil Steen Rasmussen +61 more
TL;DR: In this paper, the benefits and harms of different oxygenation levels for patients with acute hypoxemic respiratory failure in the intensive care unit (ICU) were discussed. But, the benefits of different levels of oxygenation were not evaluated.
Journal ArticleDOI
Type 2 diabetes is associated with altered NF-κB DNA binding activity, JNK phosphorylation, and AMPK phosphorylation in skeletal muscle after LPS.
TL;DR: It is indicated that pathways regulating glucose uptake in skeletal muscle may be involved in the development of inflammation-associated hyperglycemia and patients with type 2 diabetes exhibit changes in these pathways, which may ultimately render such patients more prone to develop dysregulated glucose disposal in the context of systemic inflammation.