M
Marjatta Okkonen
Researcher at University of Helsinki
Publications - 16
Citations - 691
Marjatta Okkonen is an academic researcher from University of Helsinki. The author has contributed to research in topics: Intensive care & Intensive care unit. The author has an hindex of 12, co-authored 16 publications receiving 477 citations. Previous affiliations of Marjatta Okkonen include Helsinki University Central Hospital.
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Journal ArticleDOI
Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure
Olav L. Schjørring,Thomas Lass Klitgaard,Anders Perner,Jørn Wetterslev,Theis Lange,Martin Siegemund,Minna Bäcklund,Frederik Keus,Jon Henrik Laake,Matt Morgan,Katrin Thormar,Søren A. Rosborg,Jannie Bisgaard,Annette E.S. Erntgaard,Anne Sofie H. Lynnerup,Rasmus L. Pedersen,Elena Crescioli,Theis C. Gielstrup,Meike T. Behzadi,Lone Musaeus Poulsen,Stine Estrup,Jens Laigaard,Cheme Andersen,Camilla Bekker Mortensen,Björn A. Brand,Jonathan White,Inge Lise Jarnvig,Morten Hylander Møller,Lars Quist,Morten H. Bestle,Martin Schønemann-Lund,Maj K. Kamper,Mathias Hindborg,Alexa Hollinger,Caroline E. Gebhard,Núria Zellweger,Christian S. Meyhoff,Mathias Hjort,Laura K. Bech,Thorbjørn Grøfte,Helle Bundgaard,Lars Ostergaard,Maria A. Thyø,Thomas Hildebrandt,Bülent Uslu,Christoffer Sølling,Nette Møller-Nielsen,Anne Craveiro Brøchner,Morten Borup,Marjatta Okkonen,Willem Dieperink,Ulf Gøttrup Pedersen,Anne Sofie Andreasen,Lone Buus,Tayyba N. Aslam,Robert Winding,Joerg C. Schefold,Stine B. Thorup,Susanne Iversen,Janus Engstrøm,Maj Brit Nørregaard Kjær,Bodil Steen Rasmussen +61 more
TL;DR: In this paper, the benefits and harms of different oxygenation levels for patients with acute hypoxemic respiratory failure in the intensive care unit (ICU) were discussed. But, the benefits of different levels of oxygenation were not evaluated.
Journal ArticleDOI
Acute respiratory failure in intensive care units. FINNALI: a prospective cohort study
Rita Linko,Marjatta Okkonen,Ville Pettilä,Juha Perttilä,Ilkka Parviainen,Esko Ruokonen,Jyrki Tenhunen,Tero Ala-Kokko,Tero Varpula +8 more
TL;DR: Tidal volumes are higher than recommended in the concept of lung protective strategy, however, restriction of peak airway pressure was used in the majority of ARF patients, and the incidence of ALI and ARDS seems to be lower in Finland than previously reported in other countries.
Journal ArticleDOI
Targeting two different levels of both arterial carbon dioxide and arterial oxygen after cardiac arrest and resuscitation: a randomised pilot trial
Comacare Study Grp,Pekka Jakkula,Matti Reinikainen,Johanna Hästbacka,Pekka Loisa,Marjaana Tiainen,Ville Pettilä,Jussi Toppila,Marika Lähde,Minna Bäcklund,Marjatta Okkonen,Stepani Bendel,Thomas Birkelund,Anni Pulkkinen,Jonna Heinonen,Tuukka Tikka,Markus B. Skrifvars +16 more
TL;DR: Both high-normal PaCO2 and moderate hyperoxia increased NIRS values, but the NSE concentration was unaffected, and there were no differences in other secondary outcomes.
Journal ArticleDOI
Effect of Intravenous Interferon β-1a on Death and Days Free From Mechanical Ventilation Among Patients With Moderate to Severe Acute Respiratory Distress Syndrome: A Randomized Clinical Trial
V. Marco Ranieri,Ville Pettilä,Matti K Karvonen,Juho Jalkanen,Peter Nightingale,David Brealey,Jordi Mancebo,Ricard Ferrer,Alain Mercat,Nicolò Patroniti,Michael Quintel,Jean Louis Vincent,Marjatta Okkonen,Ferhat Meziani,Giacomo Bellani,Niall S. MacCallum,Jacques Creteur,Stefan Kluge,Antonio Artigas-Raventos,Mikael Maksimow,Ilse Piippo,Kati Elima,Sirpa Jalkanen,Markku Jalkanen,Geoff Bellingan +24 more
TL;DR: Among adults with moderate or severe ARDS, intravenous IFN-β-1a administered for 6 days, compared with placebo, resulted in no significant difference in a composite score that included death and number of ventilator-free days over 28 days, and these results do not support the use of IFn-β,1a in the management of ARDS.
Journal ArticleDOI
SuPAR and PAI-1 in critically ill, mechanically ventilated patients.
Ville Jalkanen,Runkuan Yang,Rita Linko,Heini Huhtala,Marjatta Okkonen,Tero Varpula,Ville Pettilä,Ville Pettilä,Jyrki Tenhunen +8 more
TL;DR: In non-operative patients, low concentrations of suPAR were predictive for survival and high concentrations for RRT and mortality, and SuPAR may be used for screening for patients with potentially good survival.