A
Annemiek A. van der Eijk
Researcher at Erasmus University Rotterdam
Publications - 98
Citations - 5199
Annemiek A. van der Eijk is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Medicine & Hepatitis E virus. The author has an hindex of 30, co-authored 79 publications receiving 3724 citations. Previous affiliations of Annemiek A. van der Eijk include Erasmus University Medical Center & Royal Cornwall Hospital Trust.
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Journal ArticleDOI
Transmission of SARS-CoV-2 on mink farms between humans and mink and back to humans.
Bas B. Oude Munnink,Reina S. Sikkema,David F. Nieuwenhuijse,Robert Jan Molenaar,Emmanuelle Munger,Richard Molenkamp,Arco N. van der Spek,Paulien Tolsma,Ariene Rietveld,Miranda Brouwer,Noortje Bouwmeester-Vincken,Frank Harders,Renate Hakze-van der Honing,Marjolein C.A. Wegdam-Blans,Ruth Bouwstra,Corine H. GeurtsvanKessel,Annemiek A. van der Eijk,Francisca C. Velkers,Lidwien A.M. Smit,Arjan Stegeman,Wim H.M. van der Poel,Marion Koopmans +21 more
TL;DR: The SARS-CoV-2 virus was initially introduced by humans and has since evolved, most likely reflecting widespread circulation among mink in the beginning of the infection period, several weeks before detection.
Journal ArticleDOI
Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19).
Jeroen J. A. van Kampen,David A. M. C. van de Vijver,Pieter L. A. Fraaij,Bart L. Haagmans,Mart M. Lamers,Nisreen M.A. Okba,Johannes P. C. van den Akker,Henrik Endeman,Diederik Gommers,Jan J. Cornelissen,Rogier A.S. Hoek,Menno M. van der Eerden,Dennis A. Hesselink,Herold J. Metselaar,Annelies Verbon,Jurriaan E. M. de Steenwinkel,Georgina I. Aron,Eric C. M. van Gorp,Sander van Boheemen,Jolanda J.C. Voermans,Charles A. Boucher,Richard Molenkamp,Marion Koopmans,Corine H. GeurtsvanKessel,Annemiek A. van der Eijk +24 more
TL;DR: In this paper, the authors report that infectious virus shedding is detected by virus cultures in 23 of the 129 patients (17.8%) hospitalized with COVID-19, and that the median duration of shedding infectious virus is 8 days post onset of symptoms (IQR 5-11) and drops below 5% after 15.2 days after onset of symptom (95% confidence interval (CI) 13.4-17.2).
Journal ArticleDOI
An evaluation of COVID-19 serological assays informs future diagnostics and exposure assessment.
Corine H. GeurtsvanKessel,Nisreen M.A. Okba,Zsofia Igloi,Susanne Bogers,Carmen W.E. Embregts,Brigitta M. Laksono,Lonneke M. Leijten,Casper Rokx,Bart J. A. Rijnders,Janette Rahamat-Langendoen,Johannes P. C. van den Akker,Jeroen J. A. van Kampen,Annemiek A. van der Eijk,Rob van Binnendijk,Bart L. Haagmans,Marion Koopmans +15 more
TL;DR: The Wantai ELISA detecting total immunoglobulins against the receptor binding domain of SARS CoV-2, has the best overall characteristics to detect functional antibodies in different stages and severity of disease, including the potential to set a cut-off indicating the presence of protective antibodies.
Journal ArticleDOI
Rapid SARS-CoV-2 whole-genome sequencing and analysis for informed public health decision-making in the Netherlands.
Bas B. Oude Munnink,David F. Nieuwenhuijse,Mart L. Stein,Áine O'Toole,Manon R. Haverkate,Madelief Mollers,Sandra K Kamga,Claudia M. E. Schapendonk,Mark Pronk,Pascal Lexmond,Anne van der Linden,Theo M. Bestebroer,Irina Chestakova,Ronald J. Overmars,Stefan van Nieuwkoop,Richard Molenkamp,Annemiek A. van der Eijk,Corine H. GeurtsvanKessel,Harry Vennema,Adam Meijer,Andrew Rambaut,Jaap T. van Dissel,Reina S. Sikkema,Aura Timen,Marion Koopmans +24 more
TL;DR: The combination of near to real-time whole-genome sequence analysis and epidemiology resulted in reliable assessments of the extent of SARS-CoV-2 transmission in the community, facilitating early decision-making to control local transmission of the virus in the Netherlands.
Posted ContentDOI
Shedding of infectious virus in hospitalized patients with coronavirus disease-2019 (COVID-19): duration and key determinants
Jeroen J. A. van Kampen,David A. M. C. van de Vijver,Pieter L. A. Fraaij,Bart L. Haagmans,Mart M. Lamers,Nisreen M.A. Okba,Johannes P. C. van den Akker,Henrik Endeman,Diederik Gommers,Jan J. Cornelissen,Rogier A.S. Hoek,Menno M. van der Eerden,Dennis A. Hesselink,Herold J. Metselaar,Annelies Verbon,Jurriaan E. M. de Steenwinkel,Georgina I. Aron,Eric C. M. van Gorp,Sander van Boheemen,Jolanda J.C. Voermans,Charles A. Boucher,Richard Molenkamp,Marion Koopmans,Corine H. GeurtsvanKessel,Annemiek A. van der Eijk +24 more
TL;DR: Infectious virus shedding drops to undetectable levels below a viral RNA load threshold and once serum neutralizing antibodies are present, which warrants the use of quantitative viralRNA load assays and serological assays in test-based strategies to discontinue or de-escalate infection prevention and control precautions.