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Anny H. Xiang
Researcher at Kaiser Permanente
Publications - 210
Citations - 15006
Anny H. Xiang is an academic researcher from Kaiser Permanente. The author has contributed to research in topics: Gestational diabetes & Diabetes mellitus. The author has an hindex of 50, co-authored 179 publications receiving 12881 citations. Previous affiliations of Anny H. Xiang include University of Southern California & University of California, Los Angeles.
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Journal ArticleDOI
Coordinate Changes in Plasma Glucose and Pancreatic β-Cell Function in Latino Women at High Risk for Type 2 Diabetes
TL;DR: A pathogenesis for type 2 diabetes in one high-risk group that is characterized by a relatively long-term decline in acute beta-cell compensation for chronic insulin resistance that is attended by slowly rising glucose levels is defined.
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A genome-wide association study of IVGTT-based measures of first-phase insulin secretion refines the underlying physiology of type 2 diabetes variants
Andrew R. Wood,Anna Jonsson,Anne U. Jackson,Nan Wang,Nienke van Leewen,Nicholette D. Palmer,Sayuko Kobes,Joris Deelen,Lorena Boquete-Vilarino,Jussi Paananen,Alena Stančáková,Dorret I. Boomsma,Eco J. C. de Geus,Elisabeth M. W. Eekhoff,Andreas Fritsche,Mark H. H. Kramer,Giel Nijpels,Annemarie M. C. Simonis-Bik,Timon W. van Haeften,Anubha Mahajan,Michael Boehnke,Richard N. Bergman,Jaakko Tuomilehto,Francis S. Collins,Karen L. Mohlke,Karina Banasik,Karina Banasik,Christopher J. Groves,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,Ewan R. Pearson,Andrea Natali,Andrea Mari,Thomas A. Buchanan,Kent D. Taylor,Kent D. Taylor,Anny H. Xiang,Anette P. Gjesing,Niels Grarup,Hans Eiberg,Oluf Pedersen,Yii-Derr Chen,Markku Laakso,Jill M. Norris,Ulf Smith,Lynne E. Wagenknecht,Leslie J. Baier,Donald W. Bowden,Torben Hansen,Mark Walker,Richard M. Watanabe,Leen M 't Hart,Leen M 't Hart,Robert L. Hanson,Timothy M. Frayling +55 more
TL;DR: The largest genome-wide association study of first-phase insulin secretion, as measured by intravenous glucose tolerance tests, using up to 5,567 individuals without diabetes from 10 studies is performed, providing further insight into the mechanisms by which common genetic variation influences type 2 diabetes risk and glycemic traits.
Journal ArticleDOI
Coincident Linkage of Fasting Plasma Insulin and Blood Pressure to Chromosome 7q in Hypertensive Hispanic Families
L.S.-C. Cheng,Richard C. Davis,Leslie J. Raffel,Anny H. Xiang,N. Wang,M. Quiñones,P.-Z. Wen,Edgar Toscano,Justo Diaz,S. Pressman,P.C. Henderson,Stanley P. Azen,Willa A. Hsueh,Thomas A. Buchanan,Jerome I. Rotter +14 more
TL;DR: Linkage of BP, HOMA, and leptin levels to the same region suggests this locus may broadly influence traits associated with IR and supports a genetic basis for phenotypic associations in IR syndrome.
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Detailed Physiological Characterization of the Development of Type 2 Diabetes in Hispanic Women with Prior Gestational Diabetes Mellitus
TL;DR: In Hispanic women, GDM represents detection of a chronic disease process characterized by falling β-cell compensation for chronic insulin resistance, and women who are farthest along at diagnosis and/or deteriorating most rapidly are most likely to develop type 2 diabetes within 12 years after the index pregnancy.
Journal ArticleDOI
Latency analysis in epidemiologic studies of occupational exposures : Application to the colorado plateau uranium miners cohort
TL;DR: The proposed bilinear and exponential decay latency models for analyzing latency effects can provide much more information about the exposure-disease latency effects than those generally used.